Retrospective Study to Evaluate the Feasibility of Ovarian Preservation in Patients With Endometrial Carcinoma

• Conditions: Endometrial Cancer
• Interventions: Procedure: surgery

• Registration Number: NCT01560026
• Lead Sponsor: Taipei Veterans General Hospital, Taiwan

Brief Summary

Endometrial cancer is one of the most common female malignancies in the United States, and has increased in incidence in Taiwan in recent decades.A recent population-based analysis noted that 4% of endometrial cancers occurred in women aged 40 years or younger, furthermore it is up to 15% in Taiwan according to the data of cancer registry. The standard treatment of endometrial cancer results in surgical menopause and places patients at risk for the long-term sequelae of estrogen deprivation. The goal of this study was to determine the frequency of a coexisting ovarian malignancy and to evaluate the outcome of ovarian preservation in women with treatment for endometrial cancer.

Detailed Description

we reviewed the cases with early stage of endometrial cancer who have primary staging surgery between January 1989 to December 2009. The enrolled patients will be divided into two group (oophorectomy vs. ovary preservation) for analysis:the outcome and recurrence type.To evaluate the outcome of ovarian preservation in women with endometrial cancer .

Study Timeline

• Study Start: 2000-08
• Study First Submitted: 2011-06-14
• Primary Completion: 2011-12
• Status Verified: 2012-03
• Study First Submitted QC: 2012-03-20
• Study First Posted: 2012-03-21
• Last Update Submitted: 2012-03-24
• Last Update Posted: 2012-03-27
• Study Completion: 2012-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

• early stage endometrial cancer after primary surgery exclusion criteria:
• MMMT, type 2 endometrial cancer

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ovarian preservation	surgery	endometrial cancer with ovarian preservation

Primary Outcome Measures

Name	Time	Method
from the time of diagnosis to the time of disease recurrence or last follow time	disease recurrence or last follow time, up to one year	the time of diagnosis to the time of disease recurrence or last follow time

Trial Locations

Locations (1)

Taipei Veterans General Hospital; 🇨🇳 Taipei, ROC, Taiwan