NIH-AARP Diet and Health Secondary Research Study Based on OH95CN025 Data
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 入组人数
- 566,398
- 试验地点
- 2
- 主要终点
- Incident Cancer
研究概览
简要总结
Background:
The NIH and the American Association of Retired Persons (AARP) conducted a Diet and Health Study. It studied the links between diet, cancer, and cause of death in a group of middle-aged people in the U.S. Researchers want to learn more about how diet and lifestyle can affect cancer and mortality.
Objective:
To clarify links between diet, lifestyle, cancer, death, and chronic diseases.
Eligibility:
AARP members ages 50 to 71 who took part in study #OH95CN025 and lived in California, Florida, Pennsylvania, New Jersey, North Carolina, Louisiana, Atlanta, or Detroit in 1995 1996.
Design:
This study will use existing data and samples. Participants will not be contacted.
Participants personal data, like name, date of birth, and address, will be used. This data will be kept private. Their data and samples will get a unique ID.
Data from other follow-up studies will be used.
Cancer outcome data will be obtained from the 8 sample areas. Many participants have moved to Arizona, Nevada, and Texas. Data will be obtained from those states as well.
Cause of death and date of death will be obtained from the National Death Index.
Cheek swab samples were gathered from 2004 to 2005. They will be used to study the oral microbiome.
The University of Washington (UW) will be added as a study site. UW will study air pollution.
The process of linking with the Virtual Pooled Registry Cancer Linkage System will be explored. It uses one system. Right now, 11 state systems are used to get and link data.
Paper records will be stored in locked file rooms. Electronic data will be stored on secure servers.
详细描述
Study Description
The purpose of this study is to analyze the data that have been collected as part of NIH-AARP study (OH95CN025), a historical cohort; in this study we seek to continue to conduct research, but no new study activities will be requested from the study participants.
Objective
To examine relationships between diet, lifestyle, and cancers by means of a prospective cohort design
To examine relationships between diet, lifestyle, and mortality by means of a prospective cohort design
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 50 Years 至 71 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •AARP members
- •aged 50 to 71 years
- •resided in one of six states (California, Florida, Pennsylvania, New Jersey, North Carolina, and Louisiana) or in two metropolitan areas (Atlanta, Georgia and Detroit, Michigan) in 1995-1996
排除标准
- 未提供
结局指标
主要结局
Incident Cancer
时间窗: 12/31/2030
All cancers
All cause and disease specific mortality (especially cancer)
时间窗: 12/31/2030
All cause and disease specific mortality
Chronic Diseases
时间窗: 12/31/2030
Chronic diseases
次要结局
未报告次要终点
