NL-OMON36113已完成不适用
The influence of Vitamin B12 deficiency on the expression of Leber Hereditary Optic Neuropathy (LHON) - LHON and vitamin B12 deficiency
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •LHON patients:
- •-clinical characteristics of LHON
- •-proven LHON mutation
- •- recent loss of vision (not longer then half a year);Control patients:
- •- same gender as LHON patient for which will be matched
- •- same age (+/- 3 years) as LHON patient for which will be matched (but not younger then 18 years)
排除标准
- •LHON patient
- •- younger then 18 years;Control patients
- •-known optic neuropathy
- •-actual treatment by medical specialist (except ophthalmologist)
- •- known bowel disease, for which patient receives treatment
- •- actual neurological disease, for which patient is under treatment
- •- known renal dysfunction
- •- known diabetes mellitus
- •- known thyroid disease
- •- known anemia
- •- veganistic diet
- •- excess alcohol intake (> 4 units a day)
- •-pregnancy
- •- medication: gastric acid secretion inhibitors, colchicine
研究者
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