CTRI/2024/08/072661Not yet recruitingNot Applicable
A Study on Association between NT-ProBNP levels and Myocardial Dysfunction in Patients of Type 2 Diabetes Mellitus
Maulana Azad Medical College1 site in 1 country50 target enrollmentStarted: August 30, 2024Last updated:
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Maulana Azad Medical College
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- To study the association between the NT-ProBNP levels and myocardial dysfunction in patients of type 2 diabetes mellitus
Study Overview
Brief Summary
This study aims at the assessment of LV function with non-invasive techniques in type 2 diabetics using echocardiography for detecting structural and functional cardiac abnormalities which are then correlated with levels of brain natriuretic peptide (BNP) for early planning of management before passing into overt heart failure.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 99.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients aged more than 18 years of age with Type 2 Diabetes Mellitus.
Exclusion Criteria
- •Patients with a history of hypertension, significant valvular heart disease, congenital heart disease, persistent arrhythmias, and ischemic heart disease and thyroid disease.
- •The chronic intake of any drug that is known to cause cardiac disease, in the previous 6 months before inclusion (that would include chronic alcoholism, anti-cancer drugs).
- •Patients with hypertrophic cardiomyopathy and hypertrophic obstructive cardiomyopathy.
- •Patients with morbid obesity, renal failure and other major organ failure.
- •Patients in fluid overload state like in Pregnancy, Severe Anemia ( Hemoglobin less than 7gm/dl).
Outcomes
Primary Outcomes
To study the association between the NT-ProBNP levels and myocardial dysfunction in patients of type 2 diabetes mellitus
Time Frame: Patients aged more than 18 years presenting to OPD with Type 2 Diabetes Mellitus
Secondary Outcomes
- To evaluate the myocardial dysfunction in patients of Type 2 Diabetes Mellitus(At baseline, at 2 weeks)
Investigators
Dr Rajam Iyer Bhavana
Maulana Azad Medical College
Study Sites (1)
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