A cross-sectional study on comparing the effects of two techniques, Propofol Ketamine and Dexmedetomidine ketamine, in Total Intravenous Anaesthesia (TIVA)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To assess the quality of surgical anaesthesia induced by the combination of study drugs and the haemodynamic stability
研究概览
简要总结
Adults of age group between 20 to 50 years of both genders posted for elective surgeries of short procedure and short duration will be selected based on the inclusion criteria. they will be randomly divided into Group PK and Group DK will receive either propofol and ketamine or dexmedetomidine and ketamine. The duration of surgery total dose of drug requirement hemodynamic stability post operative recovery post operative pain relief wil be assess between the two groups wnd will be analysed for final interpretation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Short duration surgical procedures that can be done under Total intravenous anaesthesia
- •Patients who are under ASA-Grade I and II without any Comorbid diseases in the age group between 20-50 years.
- •Patients who are willing to participate in this study.
排除标准
- •Pediatric and Geriatric age group patients Patients who gave a history of being allergic to this group of drugs Major surgical procedures that require complex anaesthetic or interventional techniques Refusal to participate in the study.
结局指标
主要结局
To assess the quality of surgical anaesthesia induced by the combination of study drugs and the haemodynamic stability
时间窗: 1. Pre-operative baseline vital parameters | Intraoperative vital parameters and duration of anaesthesia 0.5.10,15,30,45,60 minutes
次要结局
- Post-operative recovery score & post-operative duration of analgesia, & time for rescue analgesia(By using Ramsey sedation scoring & VAS scoring postoperatively at 0,15,30,45 minutes, & hourly till 6hours or the time for rescue analgesia -whichever is earlier)
研究者
Emmima Praisy
Sree Balaji Medical College and Hospital