MANAGEMENT OF DUSHTAVRANA (NON-HEALING ULCER)BY HIGH FREQUENCY ELECTROTHERAPY AND AGNIKARMA-A COMPARATIVE RANDOMIZED CLINICAL CONTROL STUDY IN 18 TO 60 YEARS OF AGE
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- The parameters will be noted down before and after treatment.
Study Overview
Brief Summary
A minor nonhealing ulcer may also affect a person’s daily chores, making him uncomfortable and restless. Nonhealing ulcer i.e., Vrana is considered to be the primary pathology in the field of surgery. Chronic Dustavranas which are found commonly now a days become a challenge to the medical community and trying to find out solutions. Growth of micro-organism i.e., secondary infections in the nonhealing ulcer has led to the indiscriminate and irritational use of antibiotics due to which resistant strains of micro-organism developed, making the use of antibiotics futile. Sushruta the father of surgery has scientifically classified in a systemic manner the properties of the wealth of clinical material and the principles of management of Vrana which is valuable and validated even today. The classification of nonhealing ulcers, their prognostic evaluation and management, insistence on primary suturing in clean wounds, avoidance of sepsis and excision of extruded omentum and careful suturing of intestinal perforation in the management of perforation are examples cited. Sushruta has emphasized total management of the Vrana from the earliest stage of vitiation of Dosha to total recovery in which he insisted on bringing back the site of the lesion to normally in cases of Vrana treatment.
Agnikarma has been explained as one among the Anushastra & Upayantra. He further mentioned that a disease once treated by Agnikarma does not re-occur and does not get infected easily. Therefore, Agnikarma has emerged as an integral part of Ayurvedic therapeutics.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •The patients of the age group 18-60 years.
- •The patients with symptoms of Dushtavrana irrespective of its dosha E.g.Shul, Kandu, Strava, Gandh, Sparshasahtva.
- •Patients of any sex will be selected.
- •Marital Status – Both
- •Patient belonging to any socio-economic class.
Exclusion Criteria
- •Age group below 18 years and above 60 years.
- •Pregnant and lactating mother.
- •Patients with other systemic diseases such as AIDS, TB, Diabetes Mellitus, Malignancy, and Leprosy may affect the outcome of the treatment.
- •Ulcers with gangrenous changes.
- •Osteomyelitis wounds.
- •Dagdha Vrana.
Outcomes
Primary Outcomes
The parameters will be noted down before and after treatment.
Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)
1. Vedana (Severity of pain)
Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)
2. Kandu (Itching)
Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)
3. Gandh (Smell)
Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)
4. Strava (Discharge)
Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)
5. Sparshasahtva (Tenderness)
Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)
Secondary Outcomes
- 1) No improvement - 0 % relief in signs and symptoms.(2) Poor improvement - 0%-25% relief in sign and symptoms.)
Investigators
DrPravin Bhaurao Chetule
Dayabhai Maoji Majithiya Ayurved Mahavidyalaya and L.K.Ayurved Rugnalaya,Yavatmal
