Skip to main content
Clinical Trials/CTRI/2025/01/079747
CTRI/2025/01/079747Not yet recruitingNot Applicable

MANAGEMENT OF DUSHTAVRANA (NON-HEALING ULCER)BY HIGH FREQUENCY ELECTROTHERAPY AND AGNIKARMA-A COMPARATIVE RANDOMIZED CLINICAL CONTROL STUDY IN 18 TO 60 YEARS OF AGE

DMM Ayurved Mahavidyalaya,Yavatmal1 site in 1 country60 target enrollmentStarted: February 10, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
60
Locations
1
Primary Endpoint
The parameters will be noted down before and after treatment.

Study Overview

Brief Summary

A minor nonhealing ulcer may also affect a person’s daily chores, making him uncomfortable and restless. Nonhealing ulcer i.e., Vrana is considered to be the primary pathology in the field of surgery. Chronic Dustavranas which are found commonly now a days become a challenge to the medical community and trying to find out solutions. Growth of micro-organism i.e., secondary infections in the nonhealing ulcer has led to the indiscriminate and irritational use of antibiotics due to which resistant strains of micro-organism developed, making the use of antibiotics futile. Sushruta the father of surgery has scientifically classified in a systemic manner the properties of the wealth of clinical material and the principles of management of Vrana which is valuable and validated even today. The classification of nonhealing ulcers, their prognostic evaluation and management, insistence on primary suturing in clean wounds, avoidance of sepsis and excision of extruded omentum and careful suturing of intestinal perforation in the management of perforation are examples cited. Sushruta has emphasized total management of the Vrana from the earliest stage of vitiation of Dosha to total recovery in which he insisted on bringing back the site of the lesion to normally in cases of Vrana treatment.

Agnikarma has been explained as one among the Anushastra & Upayantra. He further mentioned that a disease once treated by Agnikarma does not re-occur and does not get infected easily. Therefore, Agnikarma has emerged as an integral part of Ayurvedic therapeutics.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • The patients of the age group 18-60 years.
  • The patients with symptoms of Dushtavrana irrespective of its dosha E.g.Shul, Kandu, Strava, Gandh, Sparshasahtva.
  • Patients of any sex will be selected.
  • Marital Status – Both
  • Patient belonging to any socio-economic class.

Exclusion Criteria

  • Age group below 18 years and above 60 years.
  • Pregnant and lactating mother.
  • Patients with other systemic diseases such as AIDS, TB, Diabetes Mellitus, Malignancy, and Leprosy may affect the outcome of the treatment.
  • Ulcers with gangrenous changes.
  • Osteomyelitis wounds.
  • Dagdha Vrana.

Outcomes

Primary Outcomes

The parameters will be noted down before and after treatment.

Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)

1. Vedana (Severity of pain)

Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)

2. Kandu (Itching)

Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)

3. Gandh (Smell)

Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)

4. Strava (Discharge)

Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)

5. Sparshasahtva (Tenderness)

Time Frame: 0th, 7th,14st and 21th (28th | follow up) and then Follow | up will be taken on 45th days | to observe recurrence)

Secondary Outcomes

  • 1) No improvement - 0 % relief in signs and symptoms.(2) Poor improvement - 0%-25% relief in sign and symptoms.)

Investigators

Sponsor
DMM Ayurved Mahavidyalaya,Yavatmal
Sponsor Class
Other [(Research institution and hospital)]
Responsible Party
Principal Investigator
Principal Investigator

DrPravin Bhaurao Chetule

Dayabhai Maoji Majithiya Ayurved Mahavidyalaya and L.K.Ayurved Rugnalaya,Yavatmal

Study Sites (1)

Loading locations...

Similar Trials