Asphyxia at Birth : Causes and Neonatal Outcome

Completed

Brief Summary: This is an historic cohort study based on the birth and delivery register of the HFME maternity ward. This study aim at understanding the evolution of asphyxia at birth, at all gestational ages, identifying causes and describing neonatal outcomes since 2000, when a second line strategy for foetal surveillance (fetal ECG) and systematic umbilical acid-gas cord blood were introduced in our maternity ward.

The investigator's hypothesis was that the neonatal asphyxia decrease could be due to 3 main factors including second line strategy introduction, systematic umbilical cord acid-base implementation and improvement in antenatal risk factor screening for asphyxia. The investigator's second hypothesis was that neonatal prognosis in neonates with acidosis was improved with systematic early after birth EEG evaluation, allowing early treatment and surveillance.

Recruitment & Eligibility

Inclusion Criteria

All births at the maternity ward of the hospital Femme-Mère-Enfant from 1st of january 2000 to 31 december 2016

Exclusion Criteria

Infants born after medical pregnancy termination and born out of the hospital and secondarily hospitalized in our department will be excluded

Primary Outcome Measures

Name	Time	Method
Rate of Neonatal asphyxia	2 months	Neonatal asphyxia define as fetal death, neonatal death, NICU transfer, neonatal seizure, umbilical-artery blood pH ≤ 7.05 with a base deficit ≥ 12 mmol per liter, intubation for ventilation at delivery or neonatal encephalopathy

Secondary Outcome Measures

Name	Time	Method

Locations (1): Department of obstetrics, Femme Mère Enfant Hospital
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Lyon, France

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