The investigation of the relationship between the morphology of coronary atherosclerosis and gene information in coronary artery disease patients.
Not Applicable
- Conditions
- Coronary artery disease patients
- Registration Number
- JPRN-UMIN000047125
- Lead Sponsor
- Kobe University School of Medicine, Division of Cardiovascular Medicine, Department of Internal Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
Patients taking steroids or undergoing treatment for cancer, or suffering from hepatitis B and C viruses Other patients who are deemed inappropriate by the physician in charge of the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The existence of somatic mutation in blood and coronary culprit plaques
- Secondary Outcome Measures
Name Time Method 1, The ratio of somatic mutation and the place in gene map of somatic mutation. 2, CT or MRI evaluation of coronary plaques 3, Histological evaluation 4, Single cell RNA and ATAC sequencing of blood and coronary culprit plaque samples 5, The interaction of somatic mutations and single cell RN and ATAC sequencing of blood and coronary culprit plaque samples. 6, Metabolomics in plasma