Skip to main content
MedPathMedPath Home
Clinical Trials/ISRCTN16441661
ISRCTN16441661
Completed
N/A

The efficacy of Sonographic and bIological pleurodesis indicators of Malignant PLeural Effusion (SIMPLE) -­ a randomised trial

niversity of Oxford0 sites313 target enrollmentFebruary 10, 2016
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsMalignant pleural effusionCancerSecondary malignant neoplasm of pleura

Overview

Phase
N/A
Intervention
Not specified
Conditions
Malignant pleural effusion
Sponsor
niversity of Oxford
Enrollment
313
Status
Completed
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2017 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/29225889 protocol 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34634246/ (added 12/10/2021)

Registry
who.int
Start Date
February 10, 2016
End Date
December 31, 2019
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Clinically confident diagnosis of MPE requiring pleurodesis defined as any of the following (more than one can be included):
  • •1\.1\. Histocytologically proven MPE
  • •1\.2\. Thoracic CT evidence of pleural malignancy
  • •1\.3\. Otherwise unexplained exudative effusion in the context of clinically proven cancer elsewhere
  • •2\. Written informed consent

Exclusion Criteria

  • •1\. Aged under 18 years
  • •2\. Poor prognosis (pleurodesis not offered in normal practice)
  • •3\. Irreversible contra\-indication to drain insertion

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
N/A
The efficacy of Sonographic and biological pleurodesis Indicators of Malignant Pleural Effusion (SIMPLE) - a randomised trialfluid around the lung caused by cancermalignant pleural effusion (MPE)1002765610035597
NL-OMON44184Oxford Respiratory Trials Unit, University of Oxford40
Completed
N/A
How Do We Ultrasound-Guided Popliteal Approach Sciatic Nerve Block?AdultRegional Anesthesia MorbidityAnesthesia Injection Site
NCT06372691Ankara City Hospital Bilkent92
Unknown
N/A
The Effect of Both Ultrasound and Fluoroscopy Guide Erector Spinae Plane BlocksPain, ChronicPain, Postoperative
NCT05044247National Taiwan University Hospital70
Completed
N/A
Pleuropulmonary Ultrasound With Clinical Examination to Check the Good Position of the Double Lumen Tube IntubationThoracicSurgery
NCT03836183Association Pro-arte70
Completed
N/A
Image-Guided Pleural Needle Biopsy in Pleural DiseasesBiopsyDiagnosisPleura; Exudate
NCT06541470Eskisehir Osmangazi University148