MedPath

Effects of Black Bean Pasta Consumption on Biomarkers in Young Adults

Not Applicable
Completed
Conditions
Glucose, High Blood
Interventions
Dietary Supplement: Black beans whole boiled
Dietary Supplement: White bread
Dietary Supplement: Knife Mill pasta
Dietary Supplement: Cyclone Flour Pasta
Dietary Supplement: Combo Flour Pasta
Registration Number
NCT05182190
Lead Sponsor
Iowa State University
Brief Summary

The study purpose is to determine the effect of eating three (3) different pasta flour formulations made from 100% black beans (Zenith) in a meal matrix (spaghetti sauce) on postprandial glycemic response in healthy adults.

Detailed Description

The 5 test treatments (white bread (negative control), whole black beans (positive control), and 3 different pasta formulations) will be administered randomly over five weeks. Meals will be combined with spaghetti sauce for a total available carbohydrate amount of 50g.

Venous blood samples will be collected for glucose and insulin analysis at time 0 (fasting) and at 30, 60, 90, 120, and 180 minutes post-treatment (timing of the post-treatment blood draws started at time 0 \[post-treatment\], which is when the participant starts consuming the treatment meal). Blood analysis was completed by a reputable biomarker diagnostics laboratory, Quest Diagnostics.

Anthropometric measures such as weight, height, waist circumference, and blood pressure were collected at screening and at the start of each test day. Thirteen hours before testing, participants consumed a standardized frozen meal to reduce the potential variation in glycemic responses on test day due to varying pre-evening dietary intakes. This control meal was selected by each participant before the start of the study. Each participant was provided the same frozen meal every time, since the subjects serve as their own controls. The day before test day, participants completed a 24 hour food recall, satiety, and gastrointestinal questionnaires. The morning of each test day participants completed the International Physical Activity Questionnaire (IPAQ), satiety, and gastrointestinal questionnaires.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
18
Inclusion Criteria
  • normal blood glucose
  • BMI between 20-29.9 kg/m2.
  • Chronic health conditions, e.g., hypertension, gastrointestinal disease.
Exclusion Criteria
  • Weight changes of >10% of body weight within previous 6 months
  • Pregnant or breastfeeding
  • Allergy to peas, beans, lentils, tomatoes, gluten, or latex
  • Unwillingness or inability to follow study protocol

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Control - whole black beansBlack beans whole boiledWhole boiled black beans (Zenith) in a 50 gram available carbohydrate dose
Control - White breadWhite breadCommercial white bread in a 50 gram available carbohydrate dose
Knife Mill pastaKnife Mill pastaHeat treated black bean flour made with standard Knife Mill techniques
Cyclone pastaCyclone Flour PastaBlack bean flour with lower protein made with novel compression/decompression mill
Combined pastaCombo Flour PastaBlack bean flour with medium protein made with novel compression/decompression mill
Primary Outcome Measures
NameTimeMethod
Change in baseline blood glucose over 3 hours (glycemic response)Time 0 (fasting) then every 30 minutes for 3 hours

Venous blood samples were collected via venous catheter. Whole blood samples were analyzed for glucose content and insulin at commercial laboratory.

Secondary Outcome Measures
NameTimeMethod
Change in satiety sensationTime 0 (fasting) then every 30 minutes for 3 hours

Satiety level measured using a visual analog scale (0-100) every 30 minutes postprandially. A higher score indicates greater satiety.

Trial Locations

Locations (1)

Iowa State University, Food Science and Human Nutrition Department

🇺🇸

Ames, Iowa, United States

© Copyright 2025. All Rights Reserved by MedPath