Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sepsis
- Sponsor
- Kuopio University Hospital
- Enrollment
- 273
- Locations
- 1
- Primary Endpoint
- This study evaluates epidemiology, microbiology and outcome of neutropenic fever and severe sepsis in haematological patients with special reference to the kinetics of inflammatory markers.
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The aim of this study is to find out whether inflammation markers including cardiac markers have predictive value in evaluation of pathogenesis of sepsis in neutropenic haematological patients.
Detailed Description
Adult AML and ASCT patients with neutropenic fever. Observation of possible progress to severe sepsis or septic shock. Blood sample collection on days 0-3 (from the beginning of neutropenic fever).
Investigators
Sari Hamalainen
MD, PhD
Kuopio University Hospital
Eligibility Criteria
Inclusion Criteria
- •diagnosis: acute myeloid leukaemia
- •age under 70 years
- •neutropenic fever
Exclusion Criteria
- •age above 70 years
- •no neutropenic fever
Outcomes
Primary Outcomes
This study evaluates epidemiology, microbiology and outcome of neutropenic fever and severe sepsis in haematological patients with special reference to the kinetics of inflammatory markers.
Time Frame: Within neutropenic period after treatment
This study evaluated epidemiology, microbiology and outcome of neutropenic fever and severe sepsis in haematological patients with special reference to the kinetics of specific inflammatory markers.