Decompression of Odontogenic Cysts

Completed

• Conditions: Keratocysts of the Jaw; Odontogenic Cysts; Pathology; Cysts Dental

• Registration Number: NCT06536907
• Lead Sponsor: Akdeniz University

Brief Summary

The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings.

The main question it aims to answer is:

Does decompression of cystic jaw lesions alter the histologic diagnosis?

A retrospective analysis was performed based on the comparison of initial and final histologic diagnoses of patients with an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery.

Detailed Description

The study included patients with a histologic diagnosis of an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery. The study was carried out retrospectively by means of evaluating records, surgical and histologic reports of patients. Pre- and post-decompression histologic findings were compared in effort to understand if decompression leads to alteration in histologic character and change in diagnoses of lesions.

Study Timeline

• Study Start: 2015-01-01
• Primary Completion: 2018-12-31
• Study Completion: 2023-09-01
• Status Verified: 2024-07
• Study First Submitted: 2024-07-31
• Study First Submitted QC: 2024-07-31
• Last Update Submitted: 2024-07-31
• Study First Posted: 2024-08-05
• Last Update Posted: 2024-08-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

• To have an initial diagnosis of an odontogenic cystic jaw lesion confirmed with an incisional biopsy.
• The patients must have undergone decompression and, enucleation or enucleation and peripheral ostectomy after decompression period.

Exclusion Criteria

• Previously treated patients
• The patients with missing information in medical and/or dental records
• The patients who did not adhere to follow-up protocol

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in histologic diagnosis following decompression (yes/no)	A decompression period ranging between 2 and 15 months	A comparison will be made between the initial histologic diagnosis and post-decompression definitive histologic diagnosis of the cystic jaw lesions

Trial Locations

Locations (1)

Akdeniz University; 🇹🇷 Antalya, Turkey