Influence of Positive Margins on Tumour Recurrence and Overall Survival After Gastrectomy for Gastric Cancer
Completed
- Conditions
- Stomach Neoplasms
- Interventions
- Other: Observation
- Registration Number
- NCT04439812
- Lead Sponsor
- Hospital Universitario Ramon y Cajal
- Brief Summary
Incidence of positive surgical margins after curative gastrectomy ranges from 1% to 20%. It has been suggested that positive surgical margins is an adverse prognosis factor, with a higher local recurrence and worse overall survival (OS). However, the management of these patients remains unclear.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 267
Inclusion Criteria
- all consecutive patients who underwent an oncological gastrectomy due to gastric cancer, between January 2010 and December 2018 at Ramon y Cajal University Hospital.
Exclusion Criteria
- distant disease (including patients with positive cytology), early postoperative mortality (within 30 days after surgery) and follow-up data not available. Resections in patients with palliative intent were also excluded.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description R=1 Observation Patients with positive margins after gastrectomy for gastric cancer R=0 Observation Patients without positive margins after gastrectomy for gastric cancer
- Primary Outcome Measures
Name Time Method evaluate the influence of positive margins on the tumour's recurrence and OS after gastrectomy for GC 8 years
- Secondary Outcome Measures
Name Time Method The secondary outcome was to analyse the possible confounding factors that could affect the recurrence and OS after gastrectomy. 8 years