临床试验/NCT04439812

NCT04439812已完成不适用

Influence of Positive Margins on Tumour Recurrence and Overall Survival After Gastrectomy for Gastric Cancer

Hospital Universitario Ramon y Cajal0 个研究点目标入组 267 人开始时间: 2010年1月1日最近更新: 2020年6月19日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方
入组人数: 267
主要终点: evaluate the influence of positive margins on the tumour's recurrence and OS after gastrectomy for GC

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

Incidence of positive surgical margins after curative gastrectomy ranges from 1% to 20%. It has been suggested that positive surgical margins is an adverse prognosis factor, with a higher local recurrence and worse overall survival (OS). However, the management of these patients remains unclear.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Retrospective

入排标准

性别: All
接受健康志愿者: 否

入选标准

•all consecutive patients who underwent an oncological gastrectomy due to gastric cancer, between January 2010 and December 2018 at Ramon y Cajal University Hospital.

排除标准

•distant disease (including patients with positive cytology), early postoperative mortality (within 30 days after surgery) and follow-up data not available. Resections in patients with palliative intent were also excluded.

结局指标

主要结局

evaluate the influence of positive margins on the tumour's recurrence and OS after gastrectomy for GC

时间窗: 8 years

次要结局

The secondary outcome was to analyse the possible confounding factors that could affect the recurrence and OS after gastrectomy.(8 years)

研究者

发起方

Hospital Universitario Ramon y Cajal

申办方类型

Other

责任方

Principal Investigator

主要研究者

Pablo Priego

Consultant surgeon MD, PhD. Associate Profesor of Surgery

Hospital Universitario Ramon y Cajal

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