Clinical Study of the effect of Vidangadi Ghanavati in Prameha (Diabetes Mellitus Type II).

Phase 2

Recruiting

• Conditions: Known cases of Diabetes mellitus type II or newly diagnosed cases of Diabetes mellitus type II

• Registration Number: CTRI/2015/04/005719
• Lead Sponsor: PDEAs College of ayurved and research centre nigdi pune

Brief Summary

The syndrome Diabetes Mellitus has largely been covered under the broad heading of Prameha. It is one of the most common metabolic disorder encountered in clinical practice. A number of factors are known to be important for development of Diabetes mellitus, including obesity, excessive caloric diet, and sedentary life style. Two main types of diabetes are Type I and Type II. Now it is no more a disease related to classes but it is also affecting masses.

Vidangadi Ghana Vati is a classical formulation mentioned in Bhaishajya Ratnavali that consists of Vidang, Shala, Arjun, Katphala, Kadamba, Lodhra , Asana and Kutaj. Vidanga is of Kashay, Katu rasa and ushna having Ushnaveerya. Shalvruksha has kashayras, rukshaguna and is known pramehaghna. Arjun possesses kashay rasa and is laghuruksha. Katphal is of kashay, tikta, katu rasa and ushna virya having laghuruksha guna. Kadamb which is of madhur, kashayras and Lodhra is kashay and laghu ruksha. Asana which is of Kashay, tikta rasa and laghu ruksha guna and known pamehaghna, and Kutaj which is of Tikta – Kashaya rasa, Laghu ruksha guna causes kaphaghna and kledaghna effects by shoshan karma. Hence this combination possesses properties of a potent medicine useful in Santarpan janya Prameha. To make it suitable and palatable in proposed study ghanavati of Vidangadi Kwatha will be used. Hence this study is designed to evaluate the effect of Vidangadi Ghanavati in Prameha vis a vis Diabetes Mellitus (type II).

Detailed Description

Not available

Study Timeline

• Study Start: 2015-03-26
• Last Update Posted: 2015-04-24

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1.Either a known diabetic on treatment or a newly diagnosed diabetic.
• 2.Patients presenting classical symptoms of Prameha.
• 3.Patient with fasting blood sugar up to 250 mg% and post prandial blood sugar up to 500 mg%.
• 4.Patient showing good, fair and moderate control in HbA1c test.

Exclusion Criteria

• 1.Patients with fasting blood sugar above 250 mg% and post prandial blood sugar above 500mg%.
• 2.Insulin Dependent Diabetes Mellitus (IDDM) and those who are under insulin therapy.
• 3.Pregnant and lactating mothers.
• 4.Patients with acute complications like Hyperglycemic coma, Ketoacidosis, and infections like gangrene.
• 5.Patients with chronic complications like Nephropathy, Neuropathy and Retinopathy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assesment of symptoms and effest on BSL Fasting and Post prandial, Urine sugar and glycosylated haemoglobin HbA1c	90 days (3 months)

Secondary Outcome Measures

Name	Time	Method
Assessment of Lipid profile, Body weight and body mass index.	90 days (3 months)

Trial Locations

Locations (1)

Department of Kayachikitsa, opd no 117; 🇮🇳 Pune, MAHARASHTRA, India

Department of Kayachikitsa, opd no 117

🇮🇳Pune, MAHARASHTRA, India

Dr Shailesh Vinayak Deshpande

Principal investigator

9763104451

dr.shaileshd@gmail.com