The Effect of a Perioperative Smoking Cessation Program on Rates of Smoking Cessation/Reduction and Perioperative Complications: a Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 168
- 试验地点
- 2
- 主要终点
- smoking cessation
研究概览
简要总结
The purpose of this study is to determine whether a perioperative smoking cessation program, implemented at least 3 weeks prior to elective surgery, is effective in increasing rates of smoking cessation or reduction. Intraoperative and immediate postoperative complications will also be compared.
详细描述
Previous studies have shown that patients have up to one-third fewer complications after surgery when they quit smoking at least several weeks before surgery. Nicotine replacement therapy (which relieves cravings for cigarettes) and support by healthcare professionals have been shown to help patients quit smoking, particularly when encountering a major health event (e.g. surgery). In addition, quitting smoking in preparation for surgery sometimes results in quitting for a longer period of time after surgery, giving these patients the health benefits of long-term smoking cessation such as reduced rates of cancer and heart disease.
The preadmission clinic at St. Joseph's Health Care, London, Ontario, is assessing how effective a new 'Stop Smoking' program is for patients preparing for surgery. The program will include brief counselling in the clinic, smoking cessation brochures, six weeks of free transdermal nicotine replacement therapy and a referral to the Canadian Cancer Society's Smokers' Helpline telephone advice line. Patients that are smokers and preparing for their elective surgery will be invited to join the study, then be assigned to a group that either participates in the program or not. These groups will then be compared in terms of success at quitting smoking and complication rates around the time of surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •smokers (defined as those that smoke at least 2 cigarettes per day and have smoked within the last 7 days)
- •over age 18
- •presenting to preadmission clinic at St. Joseph's Health Care at least 3 weeks prior to scheduled date of surgery
排除标准
- •less than age 18
- •poor proficiency in English language
- •breastfeeding
- •unable to consent due to severe mental illness or dementia
- •actively participating in another smoking cessation trial
结局指标
主要结局
smoking cessation
时间窗: date of surgery
Smoking cessation is defined as exhaled carbon monoxide (CO) of equal to or less than 7ppm on the day of surgery.
次要结局
- smoking cessation/reduction(day of surgery)
- Intraoperative complications and immediate post-operative complications(day of surgery)
- Time until PACU readiness for discharge / actual time in PACU(day of surgery)
- Unanticipated hospital admission(day of surgery)
- Hospital length of stay(until hospital discharge)
- Smoking cessation at 12 months(1 year)
研究者
Philip Jones
Associate Professor
Lawson Health Research Institute
