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Clinical Trials/NCT01260233
NCT01260233
Completed
Not Applicable

The Effect of a Perioperative Smoking Cessation Program on Rates of Smoking Cessation/Reduction and Perioperative Complications: a Randomized Clinical Trial.

Lawson Health Research Institute1 site in 1 country168 target enrollmentOctober 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Smoking
Sponsor
Lawson Health Research Institute
Enrollment
168
Locations
1
Primary Endpoint
smoking cessation
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The purpose of this study is to determine whether a perioperative smoking cessation program, implemented at least 3 weeks prior to elective surgery, is effective in increasing rates of smoking cessation or reduction. Intraoperative and immediate postoperative complications will also be compared.

Detailed Description

Previous studies have shown that patients have up to one-third fewer complications after surgery when they quit smoking at least several weeks before surgery. Nicotine replacement therapy (which relieves cravings for cigarettes) and support by healthcare professionals have been shown to help patients quit smoking, particularly when encountering a major health event (e.g. surgery). In addition, quitting smoking in preparation for surgery sometimes results in quitting for a longer period of time after surgery, giving these patients the health benefits of long-term smoking cessation such as reduced rates of cancer and heart disease. The preadmission clinic at St. Joseph's Health Care, London, Ontario, is assessing how effective a new 'Stop Smoking' program is for patients preparing for surgery. The program will include brief counselling in the clinic, smoking cessation brochures, six weeks of free transdermal nicotine replacement therapy and a referral to the Canadian Cancer Society's Smokers' Helpline telephone advice line. Patients that are smokers and preparing for their elective surgery will be invited to join the study, then be assigned to a group that either participates in the program or not. These groups will then be compared in terms of success at quitting smoking and complication rates around the time of surgery.

Registry
clinicaltrials.gov
Start Date
October 2010
End Date
August 2013
Last Updated
12 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Philip Jones

Associate Professor

Lawson Health Research Institute

Eligibility Criteria

Inclusion Criteria

  • smokers (defined as those that smoke at least 2 cigarettes per day and have smoked within the last 7 days)
  • over age 18
  • presenting to preadmission clinic at St. Joseph's Health Care at least 3 weeks prior to scheduled date of surgery

Exclusion Criteria

  • less than age 18
  • poor proficiency in English language
  • breastfeeding
  • unable to consent due to severe mental illness or dementia
  • actively participating in another smoking cessation trial

Outcomes

Primary Outcomes

smoking cessation

Time Frame: date of surgery

Smoking cessation is defined as exhaled carbon monoxide (CO) of equal to or less than 7ppm on the day of surgery.

Secondary Outcomes

  • smoking cessation/reduction(day of surgery)
  • Intraoperative complications and immediate post-operative complications(day of surgery)
  • Time until PACU readiness for discharge / actual time in PACU(day of surgery)
  • Unanticipated hospital admission(day of surgery)
  • Hospital length of stay(until hospital discharge)
  • Smoking cessation at 12 months(1 year)

Study Sites (1)

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