A randomized clinical trail on effectiveness of Plasma Rich in Growth Factors (PRGF) in combination with iliac autogenous bone graft versus PRGF with Demineralized Bone Matrix ( DBM) in repairing of alveolar clefts
Phase 3
Completed
- Conditions
- Repair of alveolar cleft in lip and palatal cleft patients.Cleft hard and soft palate with unilateral cleft lip
- Registration Number
- IRCT138801161790N1
- Lead Sponsor
- Vice chancellor for research of Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
1) Presence of unilateral alveolar cleft in lip and palate cleft patients, 2) The age range of 8 to 30 years, Exclusion criteria: 1) Systemic disease or congenital syndrome 2) Patients who have previously had the same operation
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Formation of bony bridge in alveolar cleft. Timepoint: 6 month. Method of measurement: Measuring of bony bridge volume in alveolar cleft in ct scan.
- Secondary Outcome Measures
Name Time Method Determining volume of bone formation. Timepoint: 6 month. Method of measurement: measuring of volume of grafted bone by ct scan.