NCT05332184已完成不适用
Cardiac T1 Mapping Enables Risk Prediction of LV Dysfunction After Surgery for Aortic Regurgitation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- Native T1
研究概览
简要总结
To assess whether cardiac T1 mapping for detection of myocardial fibrosis enables preoperative identification of patients at risk for early left ventricular dysfunction after surgery of aortic regurgitation.
详细描述
We hypothesized that a diffuse interstitial myocardial fibrosis may be present in AR patients who experience early systolic LV dysfunction after aortic valve surgery. We aimed to evaluate the association between preoperative cardiac T1 mapping for detection of myocardial fibrosis and early systolic LV dysfunction after surgery for aortic regurgitation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Consecutive patients with severe aortic regurgitation referred for aortic valve surgery were prospectively enrolled in the study.
排除标准
- •history of coronary artery disease
- •acute aortic valve disease (i.e., type A aortic dissection or infectious endocarditis)
- •common contraindications for MRI such as severe obesity and metallic foreign bodies.
结局指标
主要结局
Native T1
时间窗: baseline (Prior surgery)
Measured with MRI
次要结局
未报告次要终点
研究者
Martin Sinn
Resident
Universitätsklinikum Hamburg-Eppendorf
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