Effectiveness of Dextrose Injection for Osgood-Schlatter Disease

Phase 1

Completed

• Conditions: Osgood-Schlatter Disease
• Interventions: Procedure: Dextrose Injection; Procedure: Lidocaine Injection; Other: Usual Care

• Registration Number: NCT01300754
• Lead Sponsor: Universidad Nacional de Rosario

Brief Summary

Objective: To examine the potential of dextrose injection versus lidocaine injection versus supervised usual care to change pain/function/activity levels in adolescent athletes with Osgood-Schlatter Disease (OSD).

Detailed Description

Patients and methods: Girls ages 9-15 years old and boys ages 10-17 years old will be assigned to either therapist-supervised usual care, or to double-blind injection of 1% lidocaine solution with or without 12.5% dextrose. Injections will be administered monthly for three months. All subjects will then be offered dextrose injections monthly as needed. Change in the Nirschl Pain Phase Scale (NPPS) will serve as the primary outcome measure.

Study Timeline

• Study Start: 2006-01
• Primary Completion: 2009-09
• Study Completion: 2010-09
• Status Verified: 2011-01
• Study First Submitted: 2011-02-22
• Study First Submitted QC: 2011-02-22
• Last Update Submitted: 2011-02-22
• Study First Posted: 2011-02-23
• Last Update Posted: 2011-02-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• Age:9-15 year old girls and 10-17 year old boys
• Pain Location: Anterior knee.
• Sport Type: Jumping or kicking sport.
• Team Member with Coach: Member of and organized team with a coach.
• Imitation of exact pain and precise location to the tibial tuberosity with a single leg squat.
• At least 2 months of formal and gently progressive hamstring stretching, quads strengthening, and gradual sports reintroduction.
• Pain with sport at least 3 months.

Exclusion Criteria

• Patellofemoral crepitus
• Patellar origin tenderness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Dextrose	Dextrose Injection	-
Lidocaine	Lidocaine Injection	-
Usual Care	Usual Care	-

Trial Locations

Locations (1)

Hospital Provincial de Rosario; 🇦🇷 Rosario, Santa Fe, Argentina