Effect of exercise training on depressio

Not Applicable

Conditions: Depression Disorder.
Major depressive disorder, single episode, moderate
F32.1

Registration Number: IRCT20210617051606N1

Lead Sponsor: Razi University

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Male

Target Recruitment: 42

Inclusion Criteria

Not participation in regular exercise training over the last 6 months
Having moderate depression confirmed by a specialist
Getting the certification of no prohibition of participating in exercise training program from a specialist

Exclusion Criteria

Any other psychiatric disorder other than depression
Alcohol or substance addiction
Inability to perform exercise interventions
Cardiovascular and pulmonary diseases
Obesity (body mass index more than 30)
Refusal to give informed consent

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in serum levels of brain-derived neurotrophic factor. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: By the use of blood sample and ELISA method.;Change in quality of life. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: World health organization standard quality of life questionnaire (short version).;Change in depression severity. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: Hamilton Depression Rating Scale.;Change in cognitive flexibility. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: The 20-item cognitive flexibility inventory (Dennis and Vander Wal).

Secondary Outcome Measures

Name	Time	Method
Change in physical self-concept. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Physical self-concept questionnaire.;Change in the quality of sleep. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Pittsburgh Sleep Quality Index.;Change in anxiety. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Beck Anxiety Inventory.;Change in self-esteem. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Rosenberg’s Self-Esteem Scale.