The (i)mpact of (H)igh (I)ntensity intermittent (T)raining on health and mechanisms of insulin resistance in women with (P)oly(c)ystic (O)vary (S)yndrome: The iHIT-PCOS randomised control trial.
- Conditions
- DepressionPolycystic Ovary Syndrome Health related quality of lifeBarriers and facilitators to physical activityMetabolic and Endocrine - Other metabolic disordersPolycystic Ovary SyndromeInsulin ResistanceObesityMenstrual disturbances and ovulationDiet and Nutrition - ObesityReproductive Health and Childbirth - Other reproductive health and childbirth disorders
- Registration Number
- ACTRN12615000242527
- Lead Sponsor
- Victoria University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Stopped early
- Sex
- Female
- Target Recruitment
- 34
Must be diagnosed with Polycystic Ovary Syndrome by Rotterdam criteria as recommended criteria by both the NHMRC approved guideline for managing and treating PCOS and a recent NIH workshop with exclusion of other causes of hyperandrogenism (thyroid and prolactin disorders and non-classical congenital adrenal hyperplasia). The diagnostic criteria Polycystic Ovary syndrome include two of (i) irregular menstrual cycles (<21 or >35 days), (ii) clinical (hirsutism, acne) or biochemical (elevation of at least one circulating ovarian androgen) hyperandrogenism and (iii) Polycystic ovaries on ultrasound.Must have a BMI>25 m/kg2
Secondary causes of menstrual disturbance and hyperandrogenism, pregnancy (pregnancy test at baseline), smoking, diabetes, uncontrolled hypertension (>160/100), established CVD, renal impairment and malignancy, clinical depression, those on medications that interfere with end-points (e.g. anti-hypertensives, lipid-lowering agents) or >75min/week exercise as this is 50% of minimum recommended physical activity.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method