A Comparison of rate of speed of local anesthestic during spinal anesthesia on caesarean section and effect of sensory block and incidence of hypotension in pregnant females

Phase 2

Not yet recruiting

Conditions: Encounter for full-term uncomplicated delivery, (2) ICD-10 Condition: O94||Sequelae of complication of pregnancy, childbirth, and the puerperium,

Registration Number: CTRI/2023/09/057384

Lead Sponsor: Civil hospital

Brief Summary: Spinal anesthesia is the most common anesthesia for Caesarean section due to lower exposure of the fetus to drugs, creating profound sensory and motor block as well as low risk of pulmonary maternal aspiration. Many factors such as type of local anesthetic, dose, rate of injection, volume of subarachnoid space, patientâ€™s position play a role for adequate sensory block level in caesarean section with spinal block. Hypotension is the most common complication of spinal anesthesia. The most feared effect of hypotension is that it may lead to fetal hypoxia and acidosis by reducing uteroplacental perfusion if not treated timely. In current study, we hypothesized that there may be delay in reaching the level of sensory block with turbulent flow caused by rapid local anesthetic injection. We aimed to investigate the effects of 2 injection rates that is not close to each other to achieve a sensory block level and intraoperative maternal hypotension and any other complications in elective caesarean section surgeriese

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 60

Inclusion Criteria

1 Patients willing to consent for the study 2 Elective caesarean section delivery 3 American Society of Anaesthesiologists class I, II, III 4 Age 18 â€“ 40 years 5 Singleton pregnancy.

Exclusion Criteria

1 Pregnant patients with contraindications for spinal anaesthesia 2 Placental anomaly 3 Hypertension 4 Known case of cardiac, hepatic, renal disease, vascular disease 5 Hemodynamic instability 6 Spinal deformity â€¢Patients with weight <50kg or > 80kg and Height <140cm or >160cm.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to reach level of sensory block at T6	From Time to inject the drug & time to get level of sensory block at T6, time to achieve complete motor block

Secondary Outcome Measures

Name	Time	Method
maternal hypotension, any other complications	from time to inject the drug up to the postoperative one hour

Trial Locations

Locations (1): Civil hospital Ahmedabad
🇮🇳
Ahmadabad, GUJARAT, India
Civil hospital Ahmedabad
🇮🇳Ahmadabad, GUJARAT, India
Dr Soundharya T
Principal investigator
8056355004
sindhu66@ymail.com