The Effect of Wild Blueberry Consumption on Glucose Regulation in Healthy Adults

Not Applicable

Completed

• Conditions: Diabetes
• Interventions: Other: Placebo; Other: Blueberry

• Registration Number: NCT03192605
• Lead Sponsor: University of Prince Edward Island

Brief Summary

The objective of the study is to determine how wild blueberry consumption affects glucose regulation, gastrointestinal hormones and satiety in healthy adults.

Detailed Description

Healthy men and women (ages 21 - 65 years) were recruited to take part in a randomized, placebo controlled crossover design study. Subjects were screened to determine their health status (e.g. height, weight, body mass index, blood pressure and medical history). Subjects were randomly assigned to a sequence of two treatments with two study periods. The treatments are frozen wild blueberries and a placebo developed to match calories and fiber of the frozen wild blueberries. The subjects were asked to avoid high polyphenol foods in their typical diet for 7 days and consume one of the two treatments as a dietary intervention. After the seventh day subjects consumed a test meal along with either the wild blueberry or placebo. Blood was collected to determine glucose and satiety hormone levels.

Study Timeline

• Study Start: 2017-05-15
• Status Verified: 2017-06
• Primary Completion: 2017-06-02
• Study Completion: 2017-06-02
• Study First Submitted: 2017-06-16
• Study First Submitted QC: 2017-06-19
• Last Update Submitted: 2017-06-19
• Study First Posted: 2017-06-20
• Last Update Posted: 2017-06-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• Male or female

Exclusion Criteria

• BMI < 20 and > 30 kg/m²
• Pregnant women or women who plan on becoming pregnant during the study
• Postpartum women
• Lactating women
• Diabetes Mellitus
• Kidney disease
• Liver disease
• GI Disease
• Certain cancers
• Smokers
• Blueberry allergies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	Placebo control
Blueberry	Blueberry	150 grams wild blueberries

Primary Outcome Measures

Name	Time	Method
Glucose (mmol/L)	Change from baseline 0 hours and 2 hours	Plasma glucose

Trial Locations

Locations (1)

University of Prince Edward Island, Health Sciences; 🇨🇦 Charlottetown, Prince Edward Island, Canada