Yiqing oral liquid in the treatment of novel coronavirus infection randomized controlled clinical studies
- Conditions
- ovel coronavirus Pneumonia (COVID-19)
- Registration Number
- ITMCTR2200005961
- Lead Sponsor
- Huashan Hospital Affiliated to Fudan University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) The Ct value of both N gene and ORF gene in the nucleic acid detection of novel coronavirus infection is less than 30 (fluorescence quantitative PCR method, the limit value is 40);
(2) Age 18-85 years old;
(3) The clinical classification belongs to light, common and heavy;
(4) More than 1 high-risk factor for progression to severe/critical illness;
(5) Voluntarily sign a written informed consent.
(1) Pregnant and lactating women;
(2) Those with allergic constitution (referring to those allergic to the above drugs or foods or to the known ingredients of the drug in this trial);
(3) mentally ill, or incapable of self-awareness;
(4) Patients taking other antiviral drugs (including proprietary Chinese medicines);
(5) Mechanical ventilation is being used or is expected to be urgently needed;
(6) Patients with severe acute heart, brain, kidney, digestive tract and other diseases (such as acute heart failure, acute myocardial infarction, acute cerebrovascular disease, renal failure requiring dialysis treatment, acute gastrointestinal bleeding, etc.), ALT, AST more than 3 times the upper limit of normal;
(7) Suspected or confirmed severe active bacterial, fungal, tuberculosis or other infections (except for COVID-19);
(8) Those who have other circumstances that the investigator considers unsuitable to participate in clinical trials.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The standard rate of N gene and ORF gene Ct value in the detection of new coronavirus nucleic acid;7-day clinical symptom score;
- Secondary Outcome Measures
Name Time Method Time for the first nucleic acid to turn negative;Disease exacerbation rate;