The Clinical Profile of Parkinson Disease in Egypt

Completed

• Conditions: Parkinson's Disease

• Registration Number: NCT03383497
• Lead Sponsor: Cairo University

Brief Summary

Multi-center, retrospective observational cohort study in 4 tertiary referral centers in Cairo over the period from 2004 to 2016.

Study population. including all patients with idiopathic Parkinson disease attending. Patients were diagnosed in accordance to the United Kingdom - Parkinson Disease Society Brain Bank criteria.

Detailed Description

Retrospective, observational study that involve Medical Record Review (MRR). Data extraction and collection from medical records was organized through an electronic structured data collection form by two of authors (H.S and N.S).

The abstraction documents included; patient's age, sex, family history, age at onset, type and side of motor symptoms onset, associated non-motor manifestations. Moreover; management plan, drug history, outcome and disease progression were also verified and recorded.

During medical record reviewing (MRR); any missing documentation or poorly recorded information was managed by deleting the case.

Study Timeline

• Study Start: 2016-05
• Study First Submitted: 2016-09-12
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2017-12
• Study First Submitted QC: 2017-12-19
• Last Update Submitted: 2017-12-19
• Study First Posted: 2017-12-26
• Last Update Posted: 2017-12-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1237

Inclusion Criteria

• All patients with Parkinsonian syndromes

Exclusion Criteria

• Records with missing operationalized variables from patient records

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
time to L-Dopa start	6 - 12 months	The time to L-Dopa start from symptoms onset in relation to time of Diagnosis