Analysis of Odontogenic Keratocyst Treated With Various Modalities Over a 10-year
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Measurement of the bony cavity
研究概览
简要总结
Background The odontogenic keratocysts (OKCs) have been one of the maxillofacial region's most contentious pathological phenomena. Decompression/marsupialization (D/M), enucleation (E), enucleation + chemical cauterization with Carnoy's solution (E+CS), enucleation + peripheral ostectomy (E + PO), as opposed to enucleation + chemical cauterization with Carnoy's solution + peripheral ostectomy (E + CS + PO), were used during surgery to ensure that no epithelial remnants were left behind.
Rationale Through the management of OKC a recurrence could occur, the effectiveness of Decompression/marsupialization (D/M), Enucleation (E), Enucleation+Carnoy's solution chemical cauterization (E+CS), Enucleation+peripheral ostectomy (E+PO), Enucleation+Carnoy's solution chemical cauterization + peripheral ostectomy (E+CS + PO), will be analyzed
详细描述
Since the middle of the 20th century, the odontogenic keratocyst (OKC) has been one of the maxillofacial region's most contentious pathological phenomena. It was initially misdiagnosed as a primordial cyst. After that, because of its severe clinical behavior and tendency to recur, it was no longer considered to be a part of its classification, also known as a odontogenic tumor. Then, In 2017, the OKC are re-classified as a cystic lesion. But still there is debate about their management. So, this study will be enrolled with the following objectives: to describe how odontogenic keratocysts are managed, to Discover the most favorable approach to manage OKC with the need to stop it from happening again To categorize the odontogenic keratocyst management outcomes into to the subsequent groups: (1) total resolution, (2) partial resolution; (3) Recurrence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
盲法说明
The patients, investigators, and outcomes assessor will not be informed about the study
入排标准
- 年龄范围
- 10 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All odontogenic keratocysts that are treated by the following surgical treatment modalities:
- •Enucleation followed by peripheral ostectomy and Carnoy's solution
- •Decompression/ marsupialization
- •Enucleation
- •Enucleation and Carnoy's solution
- •Enucleation and Peripheral Ostectomy
- •Follow-up period 10 years
排除标准
- •Cases treated with resection
- •Cases showed neoplastic transformation in their pathology
- •Cyst Like lesions
结局指标
主要结局
Measurement of the bony cavity
时间窗: At the end of the postoperative ninth month
A presence of radiolucent area in the computed tomography scans
Recurrence rate
时间窗: At the end of the postoperative tenth year
The new occurrence of the previously removed odontogenic keratocyst will be documented
Healing period
时间窗: Starting from the postoperative third month up to the postoperative ninth month
The bone filling will monitored by using computed tomography scans
Recurrence rate
时间窗: At the end of the postoperative fifth year
The new occurrence of the previously removed odontogenic keratocyst will be documented
次要结局
未报告次要终点
研究者
Ghada Amin Khalifa, PhD
Professor of Maxillofacial Surgery and Diagnostic Science
Qassim University