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Clinical evaluation of Ayurvedic formulation in the Management of parikartika(Fissure in Ano)

Phase 2
Conditions
Health Condition 1: null- Patient of Anal fissure
Registration Number
CTRI/2017/06/008773
Lead Sponsor
CCRASNew Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

Patient of Fissure in Ano of either sex .

1)Patients of either sex aged 18 â??60 years.

2)Presence of Fissure in Ano

confirmed by DRE / proctoscopic

examination

3)Willing and able to participate for 06 weeks.

Exclusion Criteria

CLINICAL EVALUATION OF AYURVEDIC FORMULATION IN THE MANAGEMENT OF PARIKARTIKA (FISSURE IN ANO)

CASE REPORT FORM I â?? SCREENING

BEFORE TREATMENT

(Enter a ï?? in the appropriate box)

1.Centre Code: _____________

2.OPD No:_________________

3.Name of the Subject : _________________

4.Subject Sl. No.: _____________

5. Gender: Male (1) Female (2)

6.Age: __________years and __________ months

7.Date of birth

DD M M Y Y Y Y

8.Address:_______________________________________________________

_______________________________________________________

9.Telephone No: _______________________

10.Criteria for Inclusion Yes (1) No (0)

1)Patients of either sex aged 18 â??60 years.

2)Presence of Fissure in Ano

confirmed by DRE / proctoscopic

examination

3)Willing and able to participate for 06 weeks.

(For the inclusion â??YES to 1, 2 & 3â?? are compulsory)

11.Exclusion Criteria Yes (1) No (0)

1. Age below 18 years & above 60 years

2.Ulcerative colitis/Crohnâ??s disease

3.Patients of Malignancy/Tubercular/Syphilis/HIV/HbsAg/Bleeding disorders

4.Pregnancy and lactation

5.Patient who cannot report in person once in a week in the OPD

6.Patients with poorly controlled Hypertension( >160/100 mm Hg)

7.Patients with poorly controlled Diabetes Mellitus having HbA1C >8

8.Patients suffering from major systemic illness (Cardiac/Pulmonary/Hepatic/Renal disorders or any other conditions that may jeoparadise the study.

9.Alcoholics,Smokers and or drug abusers.

10.H/o hypersensitivity to any of the trial drugs or their ingredients.

11.Patients who have completed participation in any other clinical trial during the past six (06) months.

(For the Exclusion â??YES to any of the above)

Laboratory Examination:

ï??Haematology

oHaemoglobin : _____________________ g/dl

oT.L.C.: _____________________ / cu.mm.

oD.L.C. : N ____% E ____% B ____% L ____% M _____%

oBleeding time------------------- Clotting time----------------------

oProthrombin time------------------------------------------------------

oHIV 1 & 2----------------------------- VDRL--------------------------

oHBsAg--------------------------------------------------------------------

oE.S.R. : _________mm (at the end of 1st hour)

oBlood Sugar: Fasting ____________ mg/dl.

oBlood Sugar :Post Prandial--------------------------------

ï??Bio-chemistry:

oBlood Urea : _________________ mg/dL

oSerum

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Relief in signs and symptoms of Fissure in AnoTimepoint: 42 days
Secondary Outcome Measures
NameTimeMethod
Reducing Resting Anal pressure,Reducing Anal inflammation,Healing the ulcer,Imroving Quality of Life and Improving Bowel movementTimepoint: 42 days
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