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Sentinel lymph node detection of the head and neck cancer by contrast-enhanced ultrasonography

Phase 1
Conditions
head and neck cancer
Registration Number
JPRN-jRCTs021180036
Lead Sponsor
Shiga kiyoto
Brief Summary

This study aimed to detect sentinel lymph nodes by contrast-enhanced ultrasonography. Sentinel lymph node was detectable by contrast-enhanced ultrasonography in some of the patients. However, as the background shadow was very high in other patients, detection of the sentinel lymph nodes was not possible..

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
3
Inclusion Criteria

1. head and neck cancer patients with untreated lymph node metastasis in the neck
2. patients with the tumor which will be resected and diagnosed by histopathological examination
3. patients more than 20 years old

Exclusion Criteria

1. patients with allergy to egg or ingredient made from egg
2. patients with arterio-venous shunt in heart or lung
3. patients with severe heart disease
4. patients with severe lung disease
5. patients who will undergo laparoscopic examination or digestive tract examination using effervescent agent on the same day undergoing this examination
6. pregnant or possible pregnant patients and breast-feeding patients
7. patients who can not receive contrast-enhanced MRI or CT examination
8. patients whose target tumor are recurrent diseases
9. patients who received or will be received contrast-enhanced media (Iode media, MRI media, other contrast-enhanced media for ultrasonography etc.) during the day before and after the day of sonazoid injection
10. patients who responsible doctors recognize inappropriate for this study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Detection rate of sentinel lymph node by ultrasonography using contrast-medium
Secondary Outcome Measures
NameTimeMethod
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