JPRN-jRCTs021180036
Completed
Phase 1
Sentinel lymph node detection of the head and neck cancer patients by ultrasonography using micro-bubble contrast-medium-Phase I study of the efficacy of sonazoid targeting head and neck cancers
Shiga kiyoto0 sites3 target enrollmentStarted: March 25, 2019Last updated:
Conditionshead and neck cancer
Overview
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Shiga kiyoto
- Enrollment
- 3
Overview
Brief Summary
This study aimed to detect sentinel lymph nodes by contrast-enhanced ultrasonography. Sentinel lymph node was detectable by contrast-enhanced ultrasonography in some of the patients. However, as the background shadow was very high in other patients, detection of the sentinel lymph nodes was not possible..
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- >= 20age old to ot applicable (—)
- Sex
- All
Inclusion Criteria
- •1\. head and neck cancer patients with untreated lymph node metastasis in the neck
- •2\. patients with the tumor which will be resected and diagnosed by histopathological examination
- •3\. patients more than 20 years old
Exclusion Criteria
- •1\. patients with allergy to egg or ingredient made from egg
- •2\. patients with arterio\-venous shunt in heart or lung
- •3\. patients with severe heart disease
- •4\. patients with severe lung disease
- •5\. patients who will undergo laparoscopic examination or digestive tract examination using effervescent agent on the same day undergoing this examination
- •6\. pregnant or possible pregnant patients and breast\-feeding patients
- •7\. patients who can not receive contrast\-enhanced MRI or CT examination
- •8\. patients whose target tumor are recurrent diseases
- •9\. patients who received or will be received contrast\-enhanced media (Iode media, MRI media, other contrast\-enhanced media for ultrasonography etc.) during the day before and after the day of sonazoid injection
- •10\. patients who responsible doctors recognize inappropriate for this study
Investigators
Similar Trials
Withdrawn
Not Applicable
Feasibility Study to Develop Sentinel Lymph Node Mapping in Rectal Cancer PatientsRectal CancerNCT02112240University of Virginia
Active, not recruiting
Phase 1
Identification of lymphatic metastasis in patients with parotid gland carcinoma by means of sentinel lymph node biopsy using 68-galium-tilmanocept PET-CT.The IMP will be used for the identification of sentinel lymph node(s) in patients with parotid gland carcinoma.MedDRA version: 21.1Level: LLTClassification code 10026329Term: Malignant neoplasm of parotid glandSystem Organ Class: 100000004864MedDRA version: 20.0Level: LLTClassification code 10072873Term: Sentinel lymph node mappingSystem Organ Class: 100000004848MedDRA version: 20.1Level: LLTClassification code 10073554Term: Sentinel node biopsySystem Organ Class: 100000004848Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Surgical Procedures, Operative [E04]EUCTR2021-003068-28-NLniversity Medical Center Utrecht10
Recruiting
Phase 3
Sentinel lymph node detection of cervical occult lymph node metastases in patients with parotid gland carcinoma by means of sentinel node biopsy using 68-galium-tilmanocept PET-CT.NL-OMON51066niversitair Medisch Centrum Utrecht10
Completed
Not Applicable
Sentinel Lymph Node Detection in Early Cervical CancerCervical CancerNCT02543775University Health Network, Toronto75
Withdrawn
Early Phase 1
Sentinel Lymph Node Identification in the Axilla of Women With Breast Cancer Using Ultrasound and Iron InjectionBreast NeoplasmCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingNCT02610920Columbia University