Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 35
- 试验地点
- 2
- 主要终点
- Reduced incidence of Postoperative Atrial fibrillation
研究概览
简要总结
Atrial Fibrillation (AF) is one of the most common postoperative complications after coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on hospital resources with an estimated annual expenditure of over $1 billion. This includes the cost of pharmacological treatment and the cost of the increased length of stay. The incidence of AF is about 30-40% in CABG patients and increases with age of the patient. As the average age of the patient that undergoes CABG surgery is increasing, it is critical to find a way to prevent or reduce the incidence of this complication.
We propose a prospective, randomized, controlled study to determine the role of pulmonary vein isolation by bipolar ablation in the prevention or reduction of postoperative AF. The block- randomization plan will be used to maintain balance of the study and control arms throughout the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who require an isolated elective CABG surgery on CPB.
- •Both male and female patients of age 18 years to 90 years.
排除标准
- •Pre existing atrial fibrillation or history of previous atrial fibrillation.
- •Inability to provide informed consent.
- •Pregnant or nursing patients.
- •Reoperative sternotomy
- •Emergency CABG surgery.
结局指标
主要结局
Reduced incidence of Postoperative Atrial fibrillation
时间窗: 12 hours
次要结局
未报告次要终点
研究者
Lawrence Wei
Associate Professor
University of Pittsburgh
