跳至主要内容
临床试验/NCT00765089
NCT00765089已完成4 期

Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation

University of Pittsburgh2 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2005年12月最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
入组人数
35
试验地点
2
主要终点
Reduced incidence of Postoperative Atrial fibrillation

研究概览

简要总结

Atrial Fibrillation (AF) is one of the most common postoperative complications after coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on hospital resources with an estimated annual expenditure of over $1 billion. This includes the cost of pharmacological treatment and the cost of the increased length of stay. The incidence of AF is about 30-40% in CABG patients and increases with age of the patient. As the average age of the patient that undergoes CABG surgery is increasing, it is critical to find a way to prevent or reduce the incidence of this complication.

We propose a prospective, randomized, controlled study to determine the role of pulmonary vein isolation by bipolar ablation in the prevention or reduction of postoperative AF. The block- randomization plan will be used to maintain balance of the study and control arms throughout the study.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who require an isolated elective CABG surgery on CPB.
  • Both male and female patients of age 18 years to 90 years.

排除标准

  • Pre existing atrial fibrillation or history of previous atrial fibrillation.
  • Inability to provide informed consent.
  • Pregnant or nursing patients.
  • Reoperative sternotomy
  • Emergency CABG surgery.

结局指标

主要结局

Reduced incidence of Postoperative Atrial fibrillation

时间窗: 12 hours

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lawrence Wei

Associate Professor

University of Pittsburgh

研究点 (2)

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