Clinical and Radiological Evaluation of Movement Disorders in Multiple Sclerosis Patients.
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Al-Azhar University
- Enrollment
- 57
- Locations
- 1
- Primary Endpoint
- Determine the prevalence of movement disorders in MS patients.
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of this study is to determine the prevalence of movement disorders in MS patients.
Also,To know the clinical type of movement disorders occurring with multiple sclerosis patients and the MRI finding of those patients. Moreover, to find the correlation between the movement disorder and the different types of MS.
Detailed Description
A randomized cross-sectional study will be conducted on diagnosed multiple sclerosis patients who were diagnosed according to McDonald criteria of MS 2017 (Thompson et al. 2018). The investigators will study the prevalence of movement disorders in M.S patients, clinical type of movement disorder and the MRI findings. Data collected from patients admitted or following at Al-Azhar university hospitals at Al-Hussein and El-Sayed Galal hospitals. The included eligible patients should fulfil the following inclusion criteria: i. Full clinical history and neurological assessment. ii. Detailed multiple sclerosis history according to MS unit history sheet. iii. Detailed history of movement disorder which include clinical type of movement disorder and medication taken (or not). iv. MRI Brain and spine of the included patient will be photographed. Exclusion criteria: 1. Patients with multiple sclerosis mimics which can cause movement disorders e.g., systemic disease or overlap syndromes including systemic lupus, vasculitis, hepatic failure, renal failure, hyperthyroidism, electrolyte disturbances, Behcet's disease or CNS infection. 2. patients with primary movement disorders or related to other neurodegenerative diseases.
Investigators
Mostafa Mahmoud Hassan Meshref
Neurology physician
Al-Azhar University
Eligibility Criteria
Inclusion Criteria
- •We will study the prevalence of movement disorders in M.S patients, clinical type of movement disorder and the MRI findings. Data collected from patients admitted or following at Al-Azhar university hospitals at Al-Hussein and El-Sayed Galal hospitals. The included eligible patients should fulfil the following inclusion criteria: i. Full clinical history and neurological assessment. ii. Detailed multiple sclerosis history according to MS unit history sheet. iii. Detailed history of movement disorder which include clinical type of movement disorder and medication taken (or not).
- •iv. MRI Brain and spine of the included patient will be photographed.
Exclusion Criteria
- •1-Patients with multiple sclerosis mimics which can cause movement disorders e.g., systemic disease or overlap syndromes including systemic lupus, vasculitis, hepatic failure, renal failure, hyperthyroidism, electrolyte disturbances, Behcet's disease or CNS infection.
- •2-patients with primary movement disorders or related to other neurodegenerative diseases.
Outcomes
Primary Outcomes
Determine the prevalence of movement disorders in MS patients.
Time Frame: Through study completion, an average of 1.5 year
To know the percentage of occurance of movement disorders in MS patients.
find the correlation between the movement disorder and the different types of MS.
Time Frame: Through study completion, an average of 1.5 year
To know if there is a correlation between the movement disorder and the different types of MS.
know the clinical type of movement disorders occurring with multiple sclerosis patients and the MRI finding of those patients.
Time Frame: Through study completion, an average of 1.5 year
To know the specific semiology for each movement disorder.