MedPath

Single-probe Microwave Ablation (MWA) of Metastatic Liver Cancer

Not Applicable
Completed
Conditions
Liver Neoplasms
Interventions
Device: Microwave ablation
Device: Radiofrequency ablation
Registration Number
NCT00922181
Lead Sponsor
University Hospital, Gasthuisberg
Brief Summary

Microwave ablation (MWA) is the most recent development in the field of local ablative therapies. The aim of this study was to evaluate the variability and reproducibility of single-probe MWA versus radiofrequency ablation (RFA) of metastatic liver tumours smaller than 3 cm in patients without underlying liver disease.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
19
Inclusion Criteria
  • Unresectable metastatic liver cancer
  • No invasion of major biliary structures
  • No invasion of major vascular structures
  • ASA score < 4
  • WHO score 0-1
  • Pre-operative chemotherapy is allowed
Exclusion Criteria
  • Resectable liver metastases
  • Life expectancy less than 3 months
  • Patients with cardiac pacemaker, cerebral aneurysm clips, implanted electronic instruments or other metal materials
  • Coagulopathy with platelet count less than 50000
  • Active infectious disease
  • Age below 18 years
  • Pregnancy of breastfeeding

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
MWAMicrowave ablationPatients undergoing MWA for hepatic metastases smaller than 3 cm, without underlying liver disease
RFARadiofrequency ablationPatients undergoing RFA for hepatic metastases smaller than 3 cm, without underlying liver disease
Primary Outcome Measures
NameTimeMethod
Variability of ablation diameterswithin the first 7 days and 3 months after surgery
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University Hospital Gasthuisberg

🇧🇪

Leuven, Vlaams-Brabant, Belgium

© Copyright 2025. All Rights Reserved by MedPath