A randomised controlled trial of excisional surgery versus imiquimod 5% cream for nodular and superficial basal cell carcinoma

Phase 3

Completed

• Conditions: Topic: National Cancer Research Network; Subtopic: Melanoma; Disease: Skin; Cancer; Melanoma

• Registration Number: ISRCTN48755084
• Lead Sponsor: niversity of Nottingham (UK)

Brief Summary

2010 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/20409337 2012 results in: http://www.ncbi.nlm.nih.gov/pubmed/23035730 2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24332516

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-03-31
• Study Completion: 2010-04-23
• Last Update Posted: 12 November 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 501

Inclusion Criteria

1. Primary nodular or superficial basal cell carcinoma located in low risk area
2. Access to telephone
3. Histologically proven BCC

Male or female participants of any age were recruited.

Exclusion Criteria

1. Genetic or nevoid conditions e.g., Gorlin's syndrome
2. Morphoeic (microinfiltrative) as diagnosed clinically
3. Allergy to any of the interventions
4. Involvement in a trial of another experimental intervention
5. Life threatening disease
6. Bleeding disorders
7. Unavailable for 3 years follow-up
8. Pregnant or breastfeeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified