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Clinical Trials/NCT05308173
NCT05308173
Completed
Not Applicable

Surgical and Transcatheter Aortic Valve Replacement for Aortic Stenosis in Low-risk Elective Patients. Data From Multicenter Registry.

Nicolaus Copernicus University0 sites2,393 target enrollmentJanuary 1, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Aortic Valve Stenosis
Sponsor
Nicolaus Copernicus University
Enrollment
2393
Primary Endpoint
all-cause death
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Multicenter registry data analysis of aortic valve stenosis patients that underwent elective, isolated transcutaneous aortic valve implantation (TAVI) or surgical aortic valve replacement between 2015 and 2019. In TAVI group only transfemoral access was considered.

Detailed Description

A retrospective analysis of the Multicenter Aortic Valve Registry patients operated between 2015 and 2019 in the three departments of cardiac surgery in Poland: the Medical University of Silesia in Katowice, Medical University in Gdańsk, and Poznań, University of Medical Science. Baseline clinical, procedural, and outcome data at follow-up were entered into prespecified electronic case report forms. Follow-up status was validated by personal contact or access to Polish National Health Fund. Patients with planned concomitant intervention on coronary arteries (by bypass grafting or percutaneous intervention), other valvular interventions, arrhythmia ablation, or left atrial appendage occlusion were excluded too. In TAVI group only femoral access was considered. For SAVR any tissue or mechanical valve implantation in an aortic position with sternotomy or minimal access was included.

Registry
clinicaltrials.gov
Start Date
January 1, 2015
End Date
June 30, 2021
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Nicolaus Copernicus University
Responsible Party
Principal Investigator
Principal Investigator

Mariusz Kowalewski

PhD, M.D.

Nicolaus Copernicus University

Eligibility Criteria

Inclusion Criteria

  • Age \>18 years
  • Elective procedure
  • Aortic valve replacement with means of TAVI or SAVR

Exclusion Criteria

  • Concomitant procedures

Outcomes

Primary Outcomes

all-cause death

Time Frame: up to 6 years

death resulting from cardiovascular and non-cardiovascular causes

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