The Effectiveness of Mesotherapy (Lidocaine and Proxicam) in the Treatment of Chronic Migraine
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 27
- Locations
- 1
- Primary Endpoint
- Visual Analog Scale (VAS)
Study Overview
Brief Summary
Mesotherapy is a type of injection frequently used in clinics. It is a treatment procedure that involves the injection of some drugs under the skin or into the skin. Mesotherapy is used in musculoskeletal system diseases, but it is reported that the effects of its use in migraine are uncertain.
Detailed Description
Migraine is one of the types of headaches. For the diagnosis of chronic migraine, the headache must last more than 15 days. Nerve blocks, oral medication and neuromodulation are recommended for migraine treatment.Mesotherapy is a type of injection frequently used in clinics. It is a treatment procedure that involves the injection of some drugs under the skin or into the skin. Mesotherapy is used in musculoskeletal system diseases, but it is reported that the effects of its use in migraine are uncertain. This study was planned to show the effectiveness of mesotherapy in patients with migraine.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Masking Description
open label
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Clinical diagnosis of chronic migraine disease
Exclusion Criteria
- •Infection disease
- •Thyroid disease
- •Anemia disease
- •Systemic disease
Arms & Interventions
mesotherapy
All participants who received mesotherapy were monitored regularly for the following three months to assess their prognosis and ensure patient adherence to treatment.
Intervention: Lidocain (Drug)
Outcomes
Primary Outcomes
Visual Analog Scale (VAS)
Time Frame: 12 th week
VAS rates pain on a scale of zero to 10. It is explained to the participant that 10 points means unbearable pain, zero points means no pain, and the patient is asked to rate his pain between zero and ten. Higher scores indicate increased pain severity
The frequency of painful days per month
Time Frame: 12th week
The participant is asked how many days she/he feels pain in a month.Higher numbers indicate increased frequency of painful days
Secondary Outcomes
- Duration of attack per month(12th week)
- the number of analgesic per month(12th week)
Investigators
Elif Ozyigit
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital