Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center Study
Not Applicable
- Conditions
- Unilateral Ureteropelvic Junction Obstruction
- Registration Number
- NCT00444431
- Lead Sponsor
- University Hospital, Essen
- Brief Summary
In this randomized trial surgical therapy and surveillance of ureteropelvic junction obstruction will be compared, regarding partial renal function.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 240
Inclusion Criteria
- unilateral ureteropelvic junction obstruction
- diameter of renal pelvis greater 12 mm
- partial renal function of 35%-55% proofed by scintigraphy
- urodynamically relevant decrease in renal drainage proofed by diuresis scintigraphy at the age of 4 weeks up to 6 months
- Abscence of clinical symptoms
- Healthy contralateral kidney
Exclusion Criteria
- Global decrease in renal function
- renal dystopia
- megaureter
- vesico-ureteral reflux
- progressive hydronephrosis
- oligohydrammnion
- voiding dysfunction
- bilateral hydronephrosis
- severe chronical illness
- decrease of partial renal function of more then 5% during allocation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method partial renal function
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
University Hospital of Essen, Department of Urology
🇩🇪Essen, Nordrhein-Westfalen, Germany
University Hospital of Essen, Department of Pediatric Nephrology
🇩🇪Essen, Nordrhein-Westfalen, Germany