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Clinical Trials/NCT02879123
NCT02879123
Recruiting
Not Applicable

Assessment of Patients' Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke

Fondation Ophtalmologique Adolphe de Rothschild1 site in 1 country5,000 target enrollmentNovember 12, 2015
ConditionsStroke, Acute

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke, Acute
Sponsor
Fondation Ophtalmologique Adolphe de Rothschild
Enrollment
5000
Locations
1
Primary Endpoint
early neurological clinical recovery
Status
Recruiting
Last Updated
3 months ago

Overview

Brief Summary

This trial aims at collecting standardized data concerning the early neurological clinical recovery of patients, 3 months after endovascular treatment of an acute ischemic stroke.

Although this outcome is a major issue of patients' prognosis, it is rarely collected at this stage of their follow-up.

Detailed Description

Stroke affects 1 patient every 4 minutes in France, with around 130,000 new patients each year. Early recanalisation is a major prognostic factor and the main therapeutic target in the acute phase of this disease. The recanalisation techniques currently developed are intravenous thrombolysis, intra-arterial thrombolysis and thrombectomy (or embolectomy). These therapies can be combined. Thrombectomy involves endovascular capture of the clot obstructing the intracranial artery. Recent improvements in thrombectomy techniques have also contributed to the spread of this technique. Neurovascular units include endovascular treatment in their strategy for the early management of acute proximal occlusions of intracranial arteries in almost 1 in 3 cases. This approach is currently the subject of professional agreements. Mechanical thrombectomy has now been validated by studies showing a major reduction (-35%) in the disability associated with severe cerebral infarction and a reduction in mortality, with recanalisation rates ranging from 58 to 72%. This "recanalisation" criterion is of major importance because it largely determines the functional prognosis of patients following a cerebral infarction. Patients are often followed up in the months following the operation by the neurology department that initially treated them, and in the first few weeks they may be admitted to follow-up care units. As a result, although the clinical outcome at 3 months is a major factor in patient prognosis, this information is rarely available. The aim of this study is to obtain standardised 3-month follow-up data for a large series of patients who have undergone endovascular treatment for stroke.

Registry
clinicaltrials.gov
Start Date
November 12, 2015
End Date
May 12, 2031
Last Updated
3 months ago
Study Type
Observational
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • acute ischemic stroke
  • endovascular treatment

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

early neurological clinical recovery

Time Frame: 3 months after endovascular treatment of an acute ischemic stroke

modified RANKIN score

Study Sites (1)

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