Effect of Betamethasone in mothers with PROM
Phase 3
Recruiting
- Conditions
- Premature Rupture of Membrane.Premature rupture of membranes
- Registration Number
- IRCT20221010056141N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 200
Inclusion Criteria
Mothers with Premature rupture of membranes
At 34 to 36 weeks of pregnancy
Singleton pregnancy
Exclusion Criteria
Symptoms of chorioamnionitis in mother:fever, tachycardia
Infants small for gestational age
Infants large for gestational age
Any indication of emergency termination confirmed by fetal assessment
Maternal diabetes
Passing more than 48 hours from rupture of membrane
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie betamethasone's efficacy in preterm PROM cases at 34-36 weeks?
How does betamethasone compare to other corticosteroids in improving neonatal outcomes for PROM patients?
Are there specific biomarkers that predict maternal or neonatal response to betamethasone in 34-36 week PROM?
What are the potential adverse events of betamethasone use in mothers with PROM near term and how are they managed?
How does betamethasone's role in fetal lung maturation relate to other interventions for 34-36 week PROM?