Feasibility study for 3D pcASL in diabetic foot-related MR multi-mode perfusion imaging

Phase 1

• Conditions: Diabetic foot

• Registration Number: ITMCTR1900002597
• Lead Sponsor: CACMS Xiyuan Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1) non-diabetic group: Previously healthy, 40 ~ 75 years old, no abnormal blood glucose, blood pressure, blood lipids, heart and kidney function, and body mass index in the normal range;
(2) diabetes group: Patients with previously clinically diagnosed type 2 diabetes, aged 40 ~ 75 years, without abnormal cardiac and renal functions, can be divided into groups with no risk of diabetic foot, groups with only a precursor symptoms (such as neurological symptoms or skin changes), and groups with diabetic foot patients with ulcer according to clinical diagnosis.

Exclusion Criteria

Patients with pacemakers or severe claustrophobia, which are absolute contraindication to magnetic resonance, cannot be included in this study. In addition, the exclusion criteria for each group were:
(1) non-diabetic group: Previous history of foot surgery, trauma, fracture, etc.
Have other base disease person, be like hemal disease of narrow of lower limb hemal and occlusive wait for hemal disease;
(2) diabetes group: Patients with other basic diseases, such as vascular diseases of lower limbs such as stenosis and occlusion.

Study & Design

• Study Type: Basic Science
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood flow;