MedPath

Clinical Evaluation and Assesment of Ginigivitis Patients Treated by Yarrow Natural Extract in Compare to a Contro Group

Phase 1
Completed
Conditions
Gingivitis
Interventions
Drug: Yarrow and moringa mixture
Registration Number
NCT06070571
Lead Sponsor
Deraya University
Brief Summary

A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry and Periodontology, Dental School and Hospital, Minia university to compare the antibacterial activity of yarrow Moringa herbal combinations nanoparticles in compared to Chlorhexidine as a potential treatment for gingivitis.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • a minimum of four natural uncrowned teeth in one quadrant present
  • good general health
  • can follow instructions
Exclusion Criteria
  • were pregnant or breastfeeding
  • evidence of antibiotic use during the 4 weeks prior to the study
  • were allergic to personal care/consumer products or their ingredients

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
control groupYarrow and moringa mixtureCholorohexiden oral gargles
Intervention groupYarrow and moringa mixtureBucco-adhesive films with Yarrow and Moringa extract nanoparticles
Primary Outcome Measures
NameTimeMethod
antibacterial and anti inflammatory activitiestwo weeks

scoring of erthymia and pain (no pain=0) and the other end (worst pain=10).

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Soad A. Mohamad

🇪🇬

Minya, المنيا, Egypt

© Copyright 2025. All Rights Reserved by MedPath