Clinical Assessment of Antibacterial Anti-inflammatory Activities of Yarrow Moringa Herbal Combinations in Bucco Adhesive Films
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- antibacterial and anti inflammatory activities
研究概览
简要总结
A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry and Periodontology, Dental School and Hospital, Minia university to compare the antibacterial activity of yarrow Moringa herbal combinations nanoparticles in compared to Chlorhexidine as a potential treatment for gingivitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •a minimum of four natural uncrowned teeth in one quadrant present
- •good general health
- •can follow instructions
排除标准
- •were pregnant or breastfeeding
- •evidence of antibiotic use during the 4 weeks prior to the study
- •were allergic to personal care/consumer products or their ingredients
研究组 & 干预措施
Intervention group
Bucco-adhesive films with Yarrow and Moringa extract nanoparticles
干预措施: Yarrow and moringa mixture (Drug)
control group
Cholorohexiden oral gargles
干预措施: Yarrow and moringa mixture (Drug)
结局指标
主要结局
antibacterial and anti inflammatory activities
时间窗: two weeks
scoring of erthymia and pain (no pain=0) and the other end (worst pain=10).
次要结局
未报告次要终点