Revision Total Hip Replacement Arthroplasty and Hematologic Variables

Completed

• Conditions: Avascular Necrosis of Hip; Degenerative Hip Joint Disease
• Interventions: Other: RTHRA group

• Registration Number: NCT02951741
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

Revision total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative bleeding volume.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2016-10-24
• Study First Submitted QC: 2016-10-30
• Study First Posted: 2016-11-01
• Primary Completion: 2017-02
• Study Completion: 2017-02
• Status Verified: 2017-10
• Last Update Submitted: 2017-10-10
• Last Update Posted: 2017-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• revision total hip replacement

Exclusion Criteria

• hematologic disease
• anticoagulant medication
• American Society of Anesthesiologists physical status 4 and 5

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
RTHRA group	RTHRA group	patients undergoing revision total hip replacement

Primary Outcome Measures

Name	Time	Method
Change of FIBTEM	5 minutes before initiation of anesthesia and 5 minutes after finishing operation	FIBTEM: one of the measurements of the rotational thromboelastometry

Secondary Outcome Measures

Name	Time	Method
Hemoglobin	postoperative day 4
postoperative bleeding volume	postoperative 72 hours
volume of infused fluid during operation	Period from starting to finishing the operation (During operation, an expected average of 3 hours)	Infused total crystalloid and colloid volume during the operation will be recorded
intraoperative urine output	Period from starting to finishing the operation (During operation, an expected average of 3 hours)
transfusion units	Period from starting to finishing the operation (During operation, an expected average of 3 hours) and postoperative first day	Red blood cell
Hematocrit	postoperative day 4
Platelet count	postoperative day 4
prothrombin time_international normalized ratio	postoperative day 1
activated partial prothrombin time	postoperative day 1
fibrinogen concentration	postoperative day 1

Trial Locations

Locations (1)

Seoul National University Bundang Hospital; 🇰🇷 Seongnam-si, Gyeonggi-do, Korea, Republic of