Effectiveness of Early Insulin Degludec Administration in Combination with Continuous Intravenous Insulin Infusion in the Management of Diabetic Ketoacidosis: A Prospective Multicenter Randomized Controlled Trial
Phase 3
- Conditions
- Adults (18 or more than 18 years old) with Diabetic ketoacidosisBasal insulinDegludecDiabetic ketoacidosisRebound hyperglycemiaHypoglycemiaHypokalemiaType 1 diabetes mellitusType 2 diabetes mellitus
- Registration Number
- TCTR20230408002
- Lead Sponsor
- Pending
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Adult patients who age at least 18 years old and were diagnosed with DKA
Exclusion Criteria
Degludec allergy
Euglycemic DKA
Hemodynamic instability (need vasopressor to maintain hemodynamic status) Pregnant or breastfeeding women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to resolution of DKA When meet the complete criteria of DKA resolution Time to resolution of DKA in medical record
- Secondary Outcome Measures
Name Time Method Rebound hyperglycemia at least 12 hours after discontinuation of IV insulin infusion Routinely checked capillary blood glucose (at least 4 times per day: before meal and bedtime) after discontinuation of IV insulin infusion