Carpal Tunnel Syndrome Evaluation With Ultrasound in Rheumatoid Arthritis Patients

Completed

• Conditions: Median Nerve Entrapment
• Interventions: Diagnostic Test: Ultarsound

• Registration Number: NCT06012630
• Lead Sponsor: Burak Tayyip Dede

Brief Summary

In rheumatoid arthritis (RA) patients, the diagnosis of Carpal tunnel syndrome (CTS) was made based on clinical findings and physical examinations. Then, the cross-sectional areas of the participants' median nerves from different levels were measured. Meidolateral and anteroposterior diameter were measured at the level of the carpal tunnel inlet. Flattening ratio was calculated. wrist to forearm ratio and wrist to forearm difference were calculated. The obtained data were compared between RA with CTS, RA without CTS and healthy control.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-15
• Primary Completion: 2023-07-01
• Status Verified: 2023-08
• Study Completion: 2023-08-15
• Study First Submitted: 2023-08-17
• Study First Submitted QC: 2023-08-22
• Last Update Submitted: 2023-08-22
• Study First Posted: 2023-08-25
• Last Update Posted: 2023-08-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria
• healthy controls (HC) with no history of rheumatic diseases and CTS.
• Individuals aged 18-65 years.

Exclusion Criteria

• thoese with hypothyroidism,
• gout,
• diabetes mellitus,
• history of CTS surgery,
• upper extremity plexopathy,
• polinöropathy,
• uncontrollable fibromyalgia,
• steroid injection for CTS
• For the HC group, those with phalen or tinnel detected in at least one wrist and those with bifid median nerve detected during US evaluation were not included in the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
group:3 Healthy Control	Ultarsound	Healthy Control without rheumatologic disease and Carpal tunnel syndrome
group 2: RA with CTS	Ultarsound	Rheumatoid arthritis patients with a diagnosis of CTS based on clinical findings and physical examination
group 1: RA without CTS	Ultarsound	Rheumatoid arthritis patients without a diagnosis of CTS based on clinical findings and physical examination

Primary Outcome Measures

Name	Time	Method
Comparison of US findings among participants	6 months	Comparison of US findings among participants

Secondary Outcome Measures

Name	Time	Method
Relationship between US findings and disease activity in the patient group	6 months	The correlation between the US findings of the participants in the patient group and the CDA, which evaluates disease activity, was examined.

Trial Locations

Locations (1)

Istanbul Training and Resarch Hospital; 🇹🇷 Istanbul, Turkey