NL-OMON40778招募中不适用
Gastrointestinal stromal tumors: assessment of mutations in tumors and in circulating tumor DNA and measurement of TKI plasma exposure to optimize treatment - GIST: assessment of tumor mutations and TKI plasma exposure
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Patients diagnosed with a GIST with an indication to be treated with a TKI of whom a histological biopsy before start treatment is available.
- •- Informed consent is given
排除标准
- •- Patients of whom no tumor is available before start of first line TKI
- •- Patients that refuse a tumor biopsy in case of tumor progression
- •- Patients in whom it will not be possible to perform a biopsy in case of tumor progression (for example anti-coagulants that cannot be interrupted).
研究者
相似试验
已完成
不适用
GIST: Assessment of Tumor Mutations and TKI Plasma ExposureGastro-intestinal Stromal TumorNCT02331914University Medical Center Groningen740
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1 期
ocalized gastrointestinal stromal tumors (GIST): an exploratory open-label, multicenter, single-arm phase II study to evaluate the efficacy of 2 years of adjuvant nilotinib treatment following at least 1 year of adjuvant imatinib mesylatelocalized gastrointestinal stromal tumors (GIST)MedDRA version: 13.1Level: LLTClassification code 10062427Term: Gastrointestinal stromal tumorSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2010-022713-26-DEovartis Pharma GmbH
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撤回
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Unknown
不适用
A Study on Non-invasive Early Diagnosis of Gastrointestinal Stromal Tumors and Differentiation of Benign and Malignant NodulesGastrointestinal Stromal TumorNCT04143048The First Affiliated Hospital with Nanjing Medical University300