NL-OMON55610
Completed
Not Applicable
Symptom perception in patients with functional dyspepsia: involvement of the TRPV-1 neuropeptide pathway - Functional dyspepsia and symptom perception
Medisch Universitair Ziekenhuis Maastricht0 sites70 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Functional dyspepsia
- Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Enrollment
- 70
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy controls \<\= No gastrointestinal symptoms or history of gastrointestinal
- •disease, especially not meeting criteria for functional dyspepsia and IBS
- •(according to the ROME III criteria), Functional dyspepsia patients \<\= Patients
- •referred for upper gastrointestinal endoscopy by either general practitioners
- •or doctors from the gastroenterology outpatient clinic, meeting ROME III
- •criteria for functional dyspepsia
Exclusion Criteria
- •Healthy volunteers and functional dyspepsia patients:
- •1\. Inability to stop the intake of NSAIDs within 14 days prior to endoscopy.
- •2\. Inability to stop the intake of medication affecting gastrointestinal
- •function (e.g. proton pump inhibitors, prokinetics, laxatives) within 5 days
- •prior to endoscopy
- •3\. Current use of antidepressants
- •4\. Medical history of diabetes mellitus
- •5\. Medical history of coeliac disease
- •6\. Organic disease at upper gastrointestinal endoscopy (i.e. erosive
- •esophagitis, Barrett\*s esophagus, benign esophageal stricture, Schatzki ring,
Outcomes
Primary Outcomes
Not specified
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