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临床试验/NCT03450694
NCT03450694Unknown不适用

Role of Ultrasound in Diagnosis of Laryngeal Lesions

Assiut University0 个研究点目标入组 50 人开始时间: 2018年3月最近更新:
适应症

试验速览

阶段
不适用
入组人数
50
主要终点
role of ultrasound in diagnosis of laryngeal lesions

研究概览

简要总结

The aim of the study is to assess the efficiency and limitations of ultrasound in detecting and characterizing laryngeal anatomy and study of some laryngeal disorders and their ultrasonographic appearance.

详细描述

The larynx contains the vocal cords and serves as the opening to the tracheobronchial tree. Laryngeal lesions include: benign laryngeal tumors, contact ulcers, laryngitis, laryngeoceles, malignant laryngeal tumors, spasmodic dysphonia, vocal cord paralysis, vocal cord polyps, nodules and granulomas.

Laryngeal cancers account for about one quarter of all head and neck cancers, most of which affect the true vocal cords. Black men are affected more commonly than white men. The male to female incidence ratio is about 4:1.

Laryngeal cancer is the 19th most common cause of cancer death worldwide, with around 83,400 deaths from laryngeal cancer in 2012 (1% of total cancer deaths). Cancer of larynx is one of the most common malignancies in Europe, with about 52,000 new cases per year. The yearly incidence rate in Europe is about 8 per 100,000.

Different methods were used successfully for the diagnosis of many laryngeal diseases. Rigid endoscope was used for laryngeal evaluation with the advantage that the image is large, bright and clear which allows early diagnosis of the lesion (Shao et al, 2002).

Unfortunately, not all patients can tolerate the laryngoscope especially those with a sensitive gag reflex, patients with limit of jaw or neck mobility or patients suffering from stridor. It is also difficult in most infants and children .

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients complaining of laryngeal lesions in adult age group between age 18:65 years of both sexes.

排除标准

  • patients < 18 years
  • patients > 65 years
  • patients with spinal lesions who needs spinal immobilization

结局指标

主要结局

role of ultrasound in diagnosis of laryngeal lesions

时间窗: baseline

statistical study will be done between ultrasound and laryngoscope to assess sensitivity, specificity and accuracy of ultrasound in detecting lesions, differentiate benign from malignant lesions and reach final diagnosis of the laryngeal lesions.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mennat-Alllah Samy Abdelaziz

mennat-Allah Samy

Assiut University

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Role of Ultrasound in Laryngeal Lesions | 临床试验