B-Natriueretic Peptide as an early diagnostic factor for sepsis-induced myocardial dysfunction in comparison with Cardiac troponins I & T
Not Applicable
- Conditions
- Circulatory SystemCardiology
- Registration Number
- PACTR202108851027312
- Lead Sponsor
- Ain Shams University Hospitals
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
o Age group: adult patients aged from 21 – 60 years old
o Sex : males and females
o Admitted to ICU and Fulfilling sepsis criteria (Surviving Sepsis
Campaign 2012)
? Temp >38°C or < 36°C
? Heart rate > 90 bpm
? Respiratory rate > 20 or PaCO2 < 32 mm Hg
? WBC > 12,000/mm3, < 4,000/mm3, or > 10% bands
? Present source of infection.
? Lactate > 2 mmol/L
? SBP < 90 or SBP drop = 40 mm Hg of normal
Exclusion Criteria
o Patients with comorbid cardiac disease.
? Congenital Heart Disease.
? Ischaemic heart disease with impaired cardiac function.
? Valvular heart disease.
? Infective endo-carditis.
o Patients with comorbid renal impairment.
o Patients with advanced Malignancy.
o Post arrest patients.
o Septic shock patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method early detection of sepsis induced myocardial dysfunction
- Secondary Outcome Measures
Name Time Method Discharge