Comparison Between Dexamethasone And Dexmedetomidine As A Perineural Adjuvant In Supraclavicular Brachial Plexus Block
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare the effects of Dexmedetomidine and Dexamethasone as a perineural adjuvant to 0.5% Bupivacaine in supraclavicular brachial plexus block.
研究概览
简要总结
As per the Allocated days for each groups, participants in Group A will receive Injection Dexmedetomidine 50mcg diluted with Normal Saline upto 5ml with Injection 0.5 percent bupivacaine hydrochloride 15ml with Injection lignocaine with adrenaline 10ml,
and those in Group B will receive Injection Dexamethasone 4mg diluted with Normal Saline upto 5ml with Injection 0.5 percent bupivacaine hydrochloride 15ml with injection lignocaine with adrenaline 10ml.
Supraclavicular block will be given using landmark technique to the patients using drugs as per group under all aseptic precautions. Completion of injection will be considered as time 0
After completion of injection vital parameters will be noted.
Onset of sensory and motor blockade, duration of sensory and motor blockade will be assessed.
Sensory and motor blockade evaluation will be done every 2 min until complete sensory and motor block or till 30 min, whichever will be earlier. VAS scoring will be done post operatively every 1.5 hours till 6 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Weight 50-80 kilograms ASA grade I and II All patients scheduled for elective upper limb surgeries under supraclavicular brachial plexus block.
排除标准
- •Patient refusal for consent Age less than 18 years and more than 60 years ASA grade III and IV Patients with abnormal coagulation profile Patients with local skin site infections Patient allergic to study drugs Pregnant and lactating mothers Failure or inadaequate supraclavivular block patient will be excluded.
结局指标
主要结局
To compare the effects of Dexmedetomidine and Dexamethasone as a perineural adjuvant to 0.5% Bupivacaine in supraclavicular brachial plexus block.
时间窗: UPTO 6 hours
次要结局
- To assess the onset time and duration of sensory and motor blockade of Dexmedetomidine with 0.5% Bupivacaine for Supraclavicular brachial plexus block.(To assess the onset time and duration of sensory and motor blockade of Dexamethasone with 0.5% Bupivacaine for Supraclavicular brachial plexus block.)
研究者
Dr Neha Kumari
Peoples College Of Medical Sciences Bhopal