NCT03896841CompletedNot Applicable
Ocular Surface Disease Test Results, Corneal Biomechanical Properties, and Structural Parameters in Patients With Polycystic Ovary Syndrome
Istanbul Medeniyet University0 sites38 target enrollmentStarted: March 17, 2013Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 38
- Primary Endpoint
- Comparison of the corneal biomechanical parameter results (ocular response analyzer).
Study Overview
Brief Summary
Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy reproductive age female controls.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 19 Years to 43 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •premenopausal with PCOS
Exclusion Criteria
- •patients with external ocular disease other than dry eye complaints,
- •use of topical drops that can affect the tear film layer,
- •contact lens use histories,
- •those who received hormone therapy for 6 months,
- •those who have systemic medication or systemic disease that may affect the tear film layer and reproductive physiology,
- •previous eye surgeries,
- •smokers and alcohol users,
- •those having diseases (Cushing's syndrome or androgen-secreting tumors) causing similar clinical findings.
Outcomes
Primary Outcomes
Comparison of the corneal biomechanical parameter results (ocular response analyzer).
Time Frame: 1 year
measurement of the corneal hysteresis (CH).
Comparison of the anterior segment parameter results (Pentacam).
Time Frame: 1 year
measurement of the central corneal thickness.
Secondary Outcomes
No secondary outcomes reported
Investigators
Mustafa Hepokur
Medical Doctor, Clinical Investigator
Istanbul Medeniyet University
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