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Clinical Trials/NCT03896841
NCT03896841CompletedNot Applicable

Ocular Surface Disease Test Results, Corneal Biomechanical Properties, and Structural Parameters in Patients With Polycystic Ovary Syndrome

Istanbul Medeniyet University0 sites38 target enrollmentStarted: March 17, 2013Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
38
Primary Endpoint
Comparison of the corneal biomechanical parameter results (ocular response analyzer).

Study Overview

Brief Summary

Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy reproductive age female controls.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
19 Years to 43 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • premenopausal with PCOS

Exclusion Criteria

  • patients with external ocular disease other than dry eye complaints,
  • use of topical drops that can affect the tear film layer,
  • contact lens use histories,
  • those who received hormone therapy for 6 months,
  • those who have systemic medication or systemic disease that may affect the tear film layer and reproductive physiology,
  • previous eye surgeries,
  • smokers and alcohol users,
  • those having diseases (Cushing's syndrome or androgen-secreting tumors) causing similar clinical findings.

Outcomes

Primary Outcomes

Comparison of the corneal biomechanical parameter results (ocular response analyzer).

Time Frame: 1 year

measurement of the corneal hysteresis (CH).

Comparison of the anterior segment parameter results (Pentacam).

Time Frame: 1 year

measurement of the central corneal thickness.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Istanbul Medeniyet University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Mustafa Hepokur

Medical Doctor, Clinical Investigator

Istanbul Medeniyet University

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