Effect of prednisolon acetete drop on pupil dilation and ocular pain after cataract surgery
Phase 3
- Conditions
- Effect of topical dipped prednisolone acetate 1% on pupil dilatation and pain after uncomplicated cataract surgery.Age-related incipient cataract
- Registration Number
- IRCT20180205038617N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
In non- diabetic group: Patients over 40 years old with cortical cataract, posterior subcapsular or grade 2 to 3 nuclear sclerosis that have indication of phacoemulsification surgery with general anesthesia
In diabetic group: Patients over 40 years old with cortical cataract, posterior subcapsular or grade 2 to 3 nuclear sclerosis that have pseudoexfuliation or non proliferative diabetic retinopathy and have indication of phacoemulsification surgery with general anesthesia
Exclusion Criteria
History of previous intraocular surgery
collagen vascular disease
history of previous or current topical steroids, alphablocker or antiglaucoma medication
history of previous or current systemic steroid use
history of uveitis
mature cataract
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Horizontal pupilary diameter. Timepoint: The diameter of the pupilary horizontal diameter is measured at the beginning and at the end of the operation using caliber and is divided into two groups up and down six millimeters. Method of measurement: Caliber.;The score of post-operative pain which is measured by Visual Analog Scale for pain questionnaire. Timepoint: 24 hours after surgery. Method of measurement: Score of Visual Analog Scale for pain questionnaire.
- Secondary Outcome Measures
Name Time Method Post operative photophobia. Timepoint: 24 hours after surgery. Method of measurement: Visual Analogue Scale for pain questionnaire.;Foreign body sensation. Timepoint: 24 hours after surgery. Method of measurement: Visual Analogue Scale for pain questionnaire.;Itching. Timepoint: 24 hours after surgery. Method of measurement: Visual Analogue Scale for pain questionnaire.